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Summary Expression Gene Literature (528) GO Terms (11) Nucleotides (2207) Proteins (48) Interactants (2308) Wiki
XB-GENEPAGE-478944
Gene Symbol:
odc1

Gene Name:
ornithine decarboxylase 1

Synonyms:
xODC1 , odc , ornithine decarboxylase ( Add synonyms , Nomenclature history )

Gene Function:
rate-limiting enzyme, polyamine biosynthesis pathway

Protein Function :
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essentia...[+]


InterPro :
Bub1/Mad3 , Protein kinase ATP BS , Kinase-like dom sf , Prot kinase dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
colorectal cancer

OMIM:
COLORECTAL CANCER; CRC

External Links:
 
Xenbase Gene ID XB-GENE-478945 XB-GENE-856383 XB-GENE-17336191
Gene Symbol odc1 odc1.L odc1.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448028
379859
108718243
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine odc1 odc1.L odc1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ODC1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Odc1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Odc1 Ensembl
zebrafish
ZFIN, AGR odc1 ZFIN Ensembl
chicken
GEISHA ODC Ensembl
fruit fly
FLYBASE Odc1 Ensembl
Publications
First Increased ornithine decarboxylase activity during meiotic maturation in Xenopus laevis oocytes., Biochem Biophys Res Commun 1980  
Most Recent Ectoderm to mesoderm transition by down-regulation of actomyosin contractility., PLoS Biol 2021                                              
All View All Papers 158 paper(s) referencing morpholinos 14 paper(s) referencing OMIMs 14 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 5 terms 2 terms
PANTHER odc1
KEGG Pathways K01581 K01581 K01581
KOG [E] Ornithine decarboxylase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks odc1
Morpholinos odc1 MO1 odc1 MO1 odc1 MO1
ORFs odc1 ORF1 odc1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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