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Summary Expression Gene Literature (36) GO Terms (24) Nucleotides (79) Proteins (43) Interactants (109) Wiki
XB-GENEPAGE-478952
Gene Symbol:
agtr1

Gene Name:
angiotensin II receptor type 1

Synonyms:
AT1 , angiotensin type 1 , agtr1-a , agtr1-b ( Add synonyms , Nomenclature history )

Gene Function:
hormone receptor

Protein Function :
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
essential hypertension

OMIM:
HYPERTENSION, ESSENTIAL [+]

External Links:
 
Xenbase Gene ID XB-GENE-478953 XB-GENE-865228 XB-GENE-5969923
Gene Symbol agtr1 agtr1.L agtr1.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100170183
398763
378523
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine agtr1 agtr1.L agtr1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards AGTR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Agtr1a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
zebrafish
chicken
GEISHA AGTR1 Ensembl
fruit fly
Publications
First Novel angiotensin II antagonists distinguish amphibian from mammalian angiotensin II receptors expressed in Xenopus laevis oocytes., Mol Pharmacol 1991  
Most Recent A novel lineage of candidate pheromone receptors for sex communication in moths., Elife 2019          
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 8 terms 8 terms
PANTHER agtr1
KEGG Pathways K04166 K04166 K04166
KOG [T] G protein-coupled receptor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks agtr1
ORFs agtr1.L ORF1
Clones Horizon Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info