Gene Symbol: ttr Gene Name: transthyretin Synonyms: transthyretin, xttr Add Xenopus synonyms Gene Function: Transthyretin and related proteins Interactants: hhex(4) , pdx1(4) , ambp(3) , ins(3) , tdrd6(3) , unnamed(3) , a2m(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001103069|Xenopus (Silurana) tropicalis transthyretin (ttr), mRNA GCATACTCTGAACAAGAATGGCTTTTTTCAAGTCTTTTCTTCTCTTAGCCCTACTGGCAATTGCCTCGGAGGCTGCACCGGGACATGTTTCCCACGGTGAAGCTGACTCCAAGTGCCCCCTTATGGTAAAAGTATTGGATGCAGTGAGAGGGATCCCCGCAGCCAATCTGCTAGTGCAAGTTTTCAGGAATACAGAGGGAAACTGGGAGCTGATCTCCAGTGGAAAAACCACCGAGCTTGGAGAAATCCATAACATCATCACAGATGAGCAGTTCACTGAAGGAGTATACAAAATTGAATTTGCAACAAAGACTTTCTGGAGAAAACTTGGCCTTTCTCCATTCCATGAATATGTTGATGTGGTTTTCAGTGCTAATGACGCCGGGCATCGCCACTACACCATTGCTGTTCTGCTCACTCCCTACTCCATCTCATCCACTGCTGTTGTCAGTGAACCACACGATGATCTGTAATGACACAAAGTCCTCTTCTACAGACTACTACCATTTATGTGCAGATAATACACAGTGTTTTTTAGCTAACATTATTATTTTTTAATCTTTGTAAAACCTTCTACAGTCCAGTTCTAAGTTATGTTAACCACTGATAAATAAACCACTCTTCTGAAACAAAAAAAAAAAAAAA	Refseq >NM_001087879|Xenopus laevis transthyretin (ttr), mRNA GCATAGTGTGCACAATCGCATACACCTTCTGAACAACAATGGCTTCCTTCAAGTCTTTTCTTCTCTTAGCCCTACTGGCAATTGTCTCAGAGGCTGCACCACCGGGACATGCTTCCCATGGAGAAGCCGACTCCAAGTGTCCCCTAATGGTAAAAGTATTGGATGCAGTGAGAGGAATCCCCGCTGCCAATCTGCTAGTGAACGTTTTCAGGCAGACTGAAAGTGGAAAGTGGGAGCAGATCACTAGTGGAAAAACCACCGAGCTTGGAGAAATCCATAATCTCACTACAGATGAGCAATTCACAGAAGGAGTCTACAAAATTGAATTTGCAACAAAGGCTTTCTGGGGAAAACTTGGCCTCTCTCCCTTCCATGAATACGTTGATGTGGTGTTCACAGCTAATGATGCCGGACATCGTCAGTACACTATTGCTGTTCTGCTCACCCCCTACTCCTTCTCATCCACTGCTATTGTCAGTGAACCACACGATGATCTGTAATGAAATTAAATTTCTCTTTTACCGACTCTTTTGACTGATTATGTGCGCATAATACACAGTGTTTTTTAACTAACATTATTGTTTTTTAATCTTTTGAAACTTCCTCCAGTCTATTTCTAGGTTATGTTAACCACTGCCAAATAAACCTCTTCTGAAACAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001096539|transthyretin [Xenopus (Silurana) tropicalis] MAFFKSFLLLALLAIASEAAPGHVSHGEADSKCPLMVKVLDAVRGIPAANLLVQVFRNTEGNWELISSGKTTELGEIHNIITDEQFTEGVYKIEFATKTFWRKLGLSPFHEYVDVVFSANDAGHRHYTIAVLLTPYSISSTAVVSEPHDDL UniProtKB	Refseq >NP_001081348|transthyretin [Xenopus laevis] MASFKSFLLLALLAIVSEAAPPGHASHGEADSKCPLMVKVLDAVRGIPAANLLVNVFRQTESGKWEQITSGKTTELGEIHNLTTDEQFTEGVYKIEFATKAFWGKLGLSPFHEYVDVVFTANDAGHRQYTIAVLLTPYSFSSTAIVSEPHDDL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.69087	Xl.889
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		4 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	TTR
mouse		MGI	Ttr	All(11) Targeted, knock Out(2) Targeted, other(5)
zebrafish		ZFIN	ttr

Publications
First:		Subunit assembly and secretion of transthyretin: studies in a cell-free translation system and in microinjected Xenopus oocytes. [J Mol Endocrinol 1989]
Most recent:		The genomic structure and the expression profile of the Xenopus laevis transthyretin gene. [Gene 2012]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		carrier activity steroid binding
Biological:		transport
Cellular Component:
EC:
KOG:		[I] Transthyretin and related proteins

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.17155.2.S1_at	Xl.889.1.S1_at
Affymetrix 2.0			Xl2.889.1.S1_at

Symbol legend[+]

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