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Summary Expression Gene Literature (9) GO Terms (16) Nucleotides (94) Proteins (33) Interactants (430) Wiki
XB-GENEPAGE-479476
Gene Symbol:
cxxc4

Gene Name:
CXXC finger protein 4

Synonyms:
Idax , Xldax ( Add synonyms , Nomenclature history )

Gene Function:
dvl-binding protein, negative regulator of the wnt signaling pathway

Protein Function :
Acts as a negative regulator of the Wnt signaling pathway required for anterior neural structure formation. Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over ...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-479477 XB-GENE-17345976 XB-GENE-6465497
Gene Symbol cxxc4 cxxc4.L cxxc4.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779646
108710745
108706732
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cxxc4 cxxc4.L cxxc4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards CXXC4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cxxc4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cxxc4 Ensembl
zebrafish
cxxc4 Ensembl
chicken
GEISHA CXXC4 Ensembl
fruit fly
Publications
First Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein., Mol Cell Biol 2001  
Most Recent Role of the visual experience-dependent nascent proteome in neuronal plasticity., Elife 2018                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 3 terms 0 term
PANTHER cxxc4
KEGG Pathways K03344 [+] K03344
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cxxc4
Morpholinos cxxc4 MO1 cxxc4 MO1
ORFs cxxc4 ORF1
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

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