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XB-GENEPAGE-479826
Gene Symbol:
tal1
Gene Name: T-cell acute lymphocytic leukemia 1
Synonyms:
SCL
,
tal-1
,
bHLHa17
,
tcl5
,
stem cell leukaemia
,
xscl
( Gene Function: transcription factor Protein Function
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Transcription factor that acts synergistically with lmo2 and gata1 to specify embryonic dorsal mesoderm to a hematopoietic fate.
InterPro
![]() Interactants:
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Diseases: Disease Ontology:
acute lymphoblastic leukemia
OMIM:
LEUKEMIA, ACUTE LYMPHOBLASTIC; ALL
External Links:
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Xenbase Gene ID | XB-GENE-479827 | XB-GENE-17340145 | XB-GENE-865312 | |||||
Gene Symbol | tal1 | tal1.L | tal1.S | Chromosome | Chr4 | chr4L | chr4S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100196924
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108714298
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398028
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | tal1 | tal1.L | tal1.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
BMP-like signals are required after the midblastula transition for blood cell development., Dev Genet 1996 ![]() |
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Most Recent |
Myelopoiesis of the Amphibian Xenopus laevis Is Segregated to the Bone Marrow, Away From Their Hematopoietic Peripheral Liver., Front Immunol 2019 ![]() |
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All | View All Papers 26 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 18 terms | 1 terms | 6 terms | |||||
PANTHER | tal1 | |||||||
KEGG Pathways | K09068 | K09068 | K09068 | |||||
KOG |
[K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | tal1 | |||||||
Morpholinos | tal1 MO1 , tal1 MO2 , tal1 MO3 | tal1 MO1 , tal1 MO2 , tal1 MO3 | tal1 MO1 , tal1 MO2 , tal1 MO3 | |||||
ORFs | tal1.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



