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Summary Expression Gene Literature (426) GO Terms (22) Nucleotides (122) Proteins (38) Interactants (535) Wiki
XB-GENEPAGE-479826
Gene Symbol:
tal1

Gene Name:
T-cell acute lymphocytic leukemia 1

Synonyms:
SCL , tal-1 , bHLHa17 , tcl5 , stem cell leukaemia , xscl ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Transcription factor that acts synergistically with lmo2 and gata1 to specify embryonic dorsal mesoderm to a hematopoietic fate.


InterPro :
Glycine rcpt A2 , Glycine rcpt A , Neuro-gated channel TM sf , Neurotransmitter ion chnl CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
acute lymphoblastic leukemia

OMIM:
LEUKEMIA, ACUTE LYMPHOBLASTIC; ALL

External Links:
1/5
 
Xenbase Gene ID XB-GENE-479827 XB-GENE-17340145 XB-GENE-865312
Gene Symbol tal1 tal1.L tal1.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100196924
108714298
398028
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tal1 tal1.L tal1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TAL1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tal1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tal1 Ensembl
zebrafish
ZFIN, AGR tal1 ZFIN Ensembl
chicken
GEISHA TAL1 Ensembl
fruit fly
worm
Publications
First BMP-like signals are required after the midblastula transition for blood cell development., Dev Genet 1996              
Most Recent Myelopoiesis of the Amphibian Xenopus laevis Is Segregated to the Bone Marrow, Away From Their Hematopoietic Peripheral Liver., Front Immunol 2019                
All View All Papers 26 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 1 terms 6 terms
PANTHER tal1
KEGG Pathways K09068 K09068 K09068
KOG [K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tal1
Morpholinos tal1 MO1 , tal1 MO2 , tal1 MO3 tal1 MO1 , tal1 MO2 , tal1 MO3 tal1 MO1 , tal1 MO2 , tal1 MO3
ORFs tal1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list