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Summary Expression Gene Literature (44) GO Terms (32) Nucleotides (149) Proteins (50) Interactants (687) Wiki
XB-GENEPAGE-479867
Gene Symbol: tp63

Gene Name: tumor protein p63

Synonyms: trp63 , ket , tp73l , Xp63 , p63 , np63 ( Add synonyms , Nomenclature history )

Gene Function: transcription factor

Protein Function :
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator tha...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: ADULT syndrome [+]

OMIM: ADULT SYNDROME [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-479868 XB-GENE-865317 XB-GENE-17341311
Gene Symbol tp63 tp63.L tp63.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100497737
373640
399036
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein TrEMBL TrEMBL TrEMBL RefSeq TrEMBL TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tp63 tp63.L tp63.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TP63 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Trp63 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tp63 ZFIN Ensembl
chicken
GEISHA TP63 Ensembl
fruit fly
worm
WORMBASE
Publications
First Pathway of B1-Alu expression in microinjected oocytes: Xenopus laevis proteins associated with nuclear precursor and processed cytoplasmic RNAs., Mol Cell Biol 1988  
Most Recent The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation., Development 2020                                      
All View All Papers 6 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 31 terms 10 terms 9 terms
PANTHER tp63
KEGG Pathways K10149 K10149
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tp63
Antibodies Tp63 Ab1 , Tp63 Ab3 Tp63 Ab1 , Tp63 Ab3 Tp63 Ab3
Morpholinos tp63 MO1 , tp63 MO2 , tp63 MO3 tp63 MO1 , tp63 MO2 , tp63 MO3 tp63 MO1 , tp63 MO2 , tp63 MO3
Clones Horizon Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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