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Summary Expression Gene Literature (25) GO Terms (41) Nucleotides (113) Proteins (34) Interactants (248) Wiki
XB-GENEPAGE-480121
Gene Symbol:
hand1

Gene Name:
heart and neural crest derivatives expressed 1

Synonyms:
eHand , hand-1 ( Add synonyms , Nomenclature history )

Gene Function:
basic helix-loop-helix transcription factor

Protein Function :
Plays an essential role in cardiac morphogenesis.



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480122 XB-GENE-865344 XB-GENE-17344626
Gene Symbol hand1 hand1.L hand1.S
Chromosome Chr03 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 549497
373663
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hand1 hand1.L hand1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HAND1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hand1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hand1 Ensembl
zebrafish
chicken
GEISHA HAND1 Ensembl
fruit fly
worm
Publications
First Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development., Genes Dev 1997  
Most Recent Asymmetrically reduced expression of hand1 homeologs involving a single nucleotide substitution in a cis-regulatory element., Dev Biol 2017                  
All View All Papers 4 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 38 terms 5 terms 0 term
PANTHER hand1
KEGG Pathways K09071 K09071
KOG [K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hand1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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