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Summary Expression Gene Literature (5) GO Terms (18) Nucleotides (316) Proteins (41) Interactants (162) Wiki
XB-GENEPAGE-480200
Gene Symbol:
septin2

Gene Name:
septin 2

Synonyms:
diff6 , nedd5 , pnutl3 , septin 2 , sept2-a , sept2-b ( Add synonyms , Nomenclature history )

Gene Function:
Septin family protein (P-loop GTPase)

Protein Function :
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium. Required for the progression th...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-480201 XB-GENE-865354 XB-GENE-6255319
Gene Symbol septin2 septin2.L septin2.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100036706
398203
494757
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine septin2 septin2.L septin2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SEPTIN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Septin2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Septin2 Ensembl
zebrafish
ZFIN, AGR sept2 ZFIN Ensembl
chicken
GEISHA SEPT2 Ensembl
fruit fly
worm
Publications
First The planar cell polarity effector protein Wdpcp (Fritz) controls epithelial cell cortex dynamics via septins and actomyosin., Biochem Biophys Res Commun 2015          
Most Recent Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing., J Cell Sci 2018  
All View All Papers 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 10 terms 10 terms
PANTHER septin2
KEGG Pathways K16942 K16942 K16942
KOG [DZU] Septin family protein (P-loop GTPase)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks septin2
ORFs sept2 ORF1 , sept2 ORF2 sept2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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