sox10 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (37)

Nucleotides (72)

Interactants (177)

XB-GENEPAGE-480303

Gene Symbol: sox10 Gene Name: SRY (sex determining region Y)-box 10 Add Xenopus synonyms Gene Function: HMG-box transcription factor Interactants: ss18l1(37) , snai2(26) , sox9(21) , foxd3(13) , pax3(11) , snai1(11) , sox3(11) View All	1/6

XB-GENE-480304

XB-GENE-865362

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001100221\|Xenopus (Silurana) tropicalis SRY (sex determining region Y)-box 10 (sox10), mRNA GGATCAGGGCAGGGAACAGAGCATCATTCAGATAGAAGAACAGAGCCTCTATTACTGACACAGGACGGAGCCAGCTCACCTCCTACCACTAAGACTCAGTAGAGTGAAGTGAAGTAAGCAGGCACCATGAGTGATGACCAAAGCTTGTCCGAAGTAGAGATGAGCCCTGTTGGGTCTGAGGATCCCTCCCTCACTCCAGACCCGCTTCCCCCTCATGCTCACTCCAGTCCAGATGATGATGAAGAAACAAAAGTAAAGAAAGAGCAAGATTCAGAGGATGAGAGGTTCCCAGTGTGCATTCGTGAAGCAGTCTCCCAGGTCTTGAGCGGCTACGACTGGACGTTGGTTCCTATGCCTGTAAGGGTCAATGGTGGCAGCAAATCCAAGCCTCACGTTAAGCGGCCCATGAATGCCTTTATGGTATGGGCCCAGGCTGCACGTCGGAAACTGGCTGACCAGTATCCACATTTACATAATGCAGAGCTTAGCAAGACTCTGGGAAAACTCTGGAGGCTGTTGAATGAGAATGACAAGAGACCCTTTATAGAGGAGGCTGAAAGGCTGCGAATGCAGCACAAGAAAGACCATCCAGATTACAAGTACCAGCCTCGTAGACGGAAGAATGGAAAACCCAACCCTGGAGAGGGAGATGGGTCCTCTGAAGCTGAGGGTGGAGCTGCCTCCATACAAGCACATTACAAAAACTCCCATCTAGATCACCGACATGGTTCTCCCATGTCTGATGGGAATTCAGAGCACTCTGCAGGTCAAAGTCATGGACCCCCTACCCCACCAACAACACCAAAGACAGAGCTTCAGGCAGGAAAGTCTGATGGCAAGAGGGATGGGTCTCGTTCATTGGGAGAAGGGGGAAAACCTCACATTGATTTTGGAAATGTGGATATAGGTGAGATCAGCCATGATGTCATGGCTAATATGGAGACATTTGACGTCAATGAATTTGACCAGTACCTTCCGCCTAATGGTCATGCTGGGCACCCAAGTCACATTGGGGGTTACACTTCCAGCTATGGCCTCAGTGGAGCTCTAGCAGCTGGTCCATCTGCTTGGGCTCTGGCGAAGCAACACCCCCAAACTGACTCCAAAGCTCAAGTGAAGACAGAAAGCTCAAGTACCAGTCATTATACAGAGCAACCATCTACATCTCAGCTGACCTACACTTCACTTGGCCTTCCACATTATGGTTCAGCATTCCCCTCCATTTCCAGGCCACAGTTCGATTATGCTGACCATCAACCATCAAGTTCTTATTACAGCCATTCCTCCCAAGCATCTAGTCTCTATTCAGCCTTTTCCTACATGGGACCTCCTCAACGTCCACTTTACACTGCAATATCTGATTCTCCAAGTGTAGCTCAGTCACACAGCCCTACACATTGGGAACAGCCAGTCTATACTACACTGTCAAGACCATGAAGAGGACAAAGCTACATAACTAAGGAGGGACAGGTCCTGAAGAATAATAGGCTCCAGCATGGTCCTTTCGTAGCTCATAACCCAGGTGGAATCTGGATTCCAAAAGTATCAGTAAACCCTAGATGGTTTTTACAGACCCCTGGAAAAGACAGTGACTGGTTCTTCTTTATTGAAAAGACATAAACATAGTAGGGGTAGGATAGCAGGGCAATGCAGGGATGGGGGAAGGGAATGCATTTTTTACAAAGTTTATGGACTTGGGTCTCTTGTACAAAGGGAGGAAACTGCAACATTTGCTATACCTGTGTTTTTGATCTTAGATACTGAAGTGACATTGGAGGCTTAGGTATGTACACTCTTTGGACGATAAAACAAAAGCCTCTGACAGCCAACCAAAAGCAGCTTGACTACTTACCGAACTAACCTGGGCTGCTAGACTGTATGAAATAAGGGATAGCATGAACATCATTTTTTTTTTATGTTGGGTATTTACATGAAAGTTAGTCAACAAATAAGTATAATGCATGTTAGAATGAATGAAGTTATATCTAGCCCTCTCTCGTGCTTCAAGGGCATCAAGCAAAAACTTACTATGGACACAACACAGGCTGGAGATTCAAAACCTGCAAACTTTATTCATTGTATTGTGAATAGAGCAAGCAAATGACCTAAATGACACATTAATATGTACAGTCAGATGTCCAGAATCTAGTTTAAAAACATTCTAACACTATGTTATATGGTCAGAATTTTTCAGGGTAGGAAGTTCCACTAACCCCTTTTCATACTCTGAATACCATTTGGTCCGAGGGATCTAAGTTGCTGCGTGCCAAACATGTCATTATAACATTCAATTCTAACATCATTTTGTGGGTTAAGTGGTCAGATAGAGTGCTTTTTTCTGATTTGGTAATTTCTATTACTGCTCATTCATGATATAGTGGGAAATAAGTTGGAGGAATAAAAAAACATTATAAGAGAACAATCTAGCTAAACAAATATCCTGTTAACATGGTAGAGCCAGGAGTCGAAACACTTCACAACAAAAGCAGTGATTTTCTGATCTGAAGCTTCTGGTGCAAGAATGTTATTTTGTCTGTATCAGAGTCTTAAATACTATAATGTCTTATTTAGCTGTTATATCATGTTGTTCTCATTTCCCATGTGCAATACTCAAACAGCAGAGAGCTAGCATGTCAGTCTATTGGAACAAAATCTATAACTTGTTGTTTACATAATGACCCCCCCCCAGTTACTTGTCAACGTATGTTTAATTCTACAAGTCAGAAGTATTACAGATGGCAAAAGATGATCGCTTTCAAATGATTGTTCATATTAAGGATTCTCTGCAGTAGACATTTCCAACTCTCTTATGTTACTTTTTAGAACCATTTCCAACGTGGGAAATACAGAGGATACTATGAAGTATGTTTTTCAGGATGAAAAAAAAAAAAAAAA	Refseq >NM_001088889\|Xenopus laevis SRY (sex determining region Y)-box 10 (sox10), mRNA GGCACGAGGGAAGAACAGAGGCTCTATTACTGACACACGACGGAGCCAGCTCACCTCCTTCCACTAAGACTCAGTAGAGTGATTCAGTGAAGTTAACAGGCACCATGAGTGATGACCAAAGCTTGTCCGAAGTAGAGATGAGCCCTGTTGGGTCTGAGGATCCCTCCCTGACTCCAGACCCGCTTCCCCCTCATGCTCACTCCAGTCCAGATGATGATGATGATGATGATGAAGAAGAAGAAGAAGAAACAAAAGTAAAGAAAGAGCAGGATTCAGAGGATGAGAGGTTTCCTGTGTGCATTCGTGAAGCAGTCTCACAGGTGTTAAATGGCTACGACTGGACATTGGTTCCTATGCCTGTAAGGGTCAATGGTGGCAGCAAATCTAAGCCTCACGTTAAGCGGCCAATGAATGCCTTTATGGTATGGGCCCAGGCTGCACGCCGGAAACTGGCTGACCAGTACCCACATTTACACAATGCAGAGCTTAGCAAGACTCTGGGTAAACTTTGGAGACTATTGAATGAGAATGACAAGAGACCCTTTATAGAGGAGGCTGAGAGGCTGCGAATGCAGCATAAGAAGGACCACCCAGATTACAAGTACCAGCCTCGTAGACGGAAGAATGGAAAACCCAGCCCTGGAGAAGGAGATGGGTCCTCTGAAGCCGAGGGTGGAGCTGCCTCCATACAAGCACATTACAAAAACTCCCATCTAGATCACCGACATGGTTCTCCCATGTCTGATGGAAATTCAGAGCACTCTACAGGTCAAAGTCATGGACCCCCTACCCCACCAACAACACCAAAGACAGAGCTTCAGGCAGGAAAGTCTGATGGCAAGAGGGATGGTTCTCATGCATTGAGAGAAGGTGGAAAACCTCAAATTGATTTTGGAAATGTGGATATAGGTGAGATCAGCCATGATGTCATGTCCAATATGGAGACATTTGACGTAAATGAATTTGACCAGTACCTTCCACCTAATGGTCATGCTGGGCACCCAAGTCACATTGGGGGCTACACCTCCAGCTATGGCCTCACTGGAGCTCTAGCAGCTGGTCCATCTGCTTGGGCTCTGGCGAAGCAACACTCTCAAACTGTGGCAGACTCTAAAGCTCAAGTGAAAACAGAAAGCTCAAGTACCAGCCATTATACAGAGCAACCCTCTACATCTCAGCTGACCTACACTTCACTTGGCCTTCCACATTATGGTTCAGCATTTCCCTCCATCTCCAGGCCACAGTTTGATTATGCTGACCATCAGCCATCAAGTTCTTATTACAGCCATTCGGCCCAAGCCTCAAGTCTCTATTCAGCCTTTTCCTACATGGGACCTCCTCAACGTCCACTCTACACTGCAATATCTGATCCTCCAAGTGTAGCTCAGTCACATAGCCCTACACATTGGGAACAGCCAGTCTATACTACACTTTCAAGACCATGAAGAGAACAGACGAACATAAATAGGGATGGACAAGTCCTGGAGAGCAATATGCTCCAGCAGGGTTCTTTTGTAGCTCATAACCCGGGCGGAATCTGGATTCCAAGGGTATCAGTAAACCCTAGTAGCTGTTTTTTTACAGACCCTTTGAAAAGACTTTGACTGGTTATTCTTTTCAAAAAAGACATAAACATAGTAGGGGTAGCATAGCAGGGCAATGCAGGGATGGGGGAAGGGAATGCAATGTATACAAAGTTTATGGACTTTTGTCTCTTGTACAAAGGGAGGAAGCTGCAACATTTGCTATACCTGTGTTTTTGATCCTAGATACTGAAGTGACATTGGAAGATTTGGTACCTACACCTTTTGGGCGATAAAAACAAAAGCCTCTGACAGCCAACCAAAAGCAGCTTGACTACTTACAGAACTAACCTGGGCTGCTAAACTGTATGAAATAAGGGACAGCATAAGGTTTCTTATCTTGGGTATTGACATGAAAGTTAGTCAACAAATAAGTATAATGCATGTTAGAATCTGAAAAATGAAGTTATTTCTAGCAGAGTCCTCTTGTTTCTAGGGTCTTCAAACCGAAGCATATGATGGACACAGCATAGTCATACTCAAAAAAAACCCTGCAAACTTTATCCATTGTACTGTGAACACAGCATGCAAATTAATATGTCAGAATCTGGCTGGAAAACACATCACTAGAAAACAAACACTATGTACACCTTTTACATGGTCAGTTGGCCATAATTTTCCAGGGTAGAAAGTTCCAATAACTGCTTTTCATGCTGTAAATAATATCATACGGTCAGAAGGATCTAAGTTGTTGCGTGCCAAATGTGTCATTATAACATTTTAGAACCAATCAGCATTTTGAAGGGAAAGGATCCGTTGGACCACTTTTCTCTGATTTGTCAATTCGTTCACTGCTCATTCATGATCCATTGGAAAATATAAGTTAGAGAAATGCAACATTATCGGAGAACAATTTAGAAGTGTACCAGACAAACATCCTTTTAGAATGGTAGAGCCAGGAGTCCGAACACAAAAGTAATGATTTTTTAACTTGAAGCTTTTGTTCACACTGATCTCCTGTGCAATACTCAAACAGCTGAGAGGTAGCATTTCAGTCCATAAGAACAAATACTATGACCTGCTGTTTACATAATGACCCCCCAATTATTTGTCAATTCATCTTTAACATTCACAACAGTCAGACGTATCGCAGATGGCAAACGATGATCTCTTTCAAATGACTGCTCATATTAAGGATTCTCTGCAGTAGACATTATCAACTCTCTTATGCTACTTAATAGAAATATTTCCAGCGTGGGAAATACAGAGGATACTATGAAGTATGTTTTTCAGGATGAAAAAATGGGAAAAAAAAAGTAGAGCCAATGTGTAAATATAAAACTATATATTCGGTATATATATATCTATTTTTATTTGTTTTGGGGGCAGCAATGTAAAGGCCGGTGCTTCTAATCCTGTGGGTAGCAGAGAGGATTATATAGAACTGGGCCACTGGATTAAACCAAACCAGTGAACTTTGGGTTTAACATTTTTTTGGGGGGGGGGGGGGGGCGGGTTTTGTTACGAAGAGGGACAGAAATCCATTAACCCATTTGGAGTTACTTCTTTTAATGCTTTGCTGTATACAAATATTAACTCCGATGTATAACATAAGTTGTCCCTTCCTCCATCACTTTTCATTCATTTAGCAAAATGATTGTTTTTGCCATTATTTCATATATATGTAACTGTATGTTTGTTATTTATGTAAATATTATCTTACCCAATTCTGGTAATTTCTTTAACTGTTCATAAACATATTCAAGATATATATTGAATTAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001093691\|transcription factor Sox-10 [Xenopus (Silurana) tropicalis] MSDDQSLSEVEMSPVGSEDPSLTPDPLPPHAHSSPDDDEETKVKKEQDSEDERFPVCIREAVSQVLSGYDWTLVPMPVRVNGGSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNENDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKPNPGEGDGSSEAEGGAASIQAHYKNSHLDHRHGSPMSDGNSEHSAGQSHGPPTPPTTPKTELQAGKSDGKRDGSRSLGEGGKPHIDFGNVDIGEISHDVMANMETFDVNEFDQYLPPNGHAGHPSHIGGYTSSYGLSGALAAGPSAWALAKQHPQTDSKAQVKTESSSTSHYTEQPSTSQLTYTSLGLPHYGSAFPSISRPQFDYADHQPSSSYYSHSSQASSLYSAFSYMGPPQRPLYTAISDSPSVAQSHSPTHWEQPVYTTLSRP UniProtKB	Refseq >NP_001082358\|transcription factor Sox-10 [Xenopus laevis] MSDDQSLSEVEMSPVGSEDPSLTPDPLPPHAHSSPDDDDDDDEEEEEETKVKKEQDSEDERFPVCIREAVSQVLNGYDWTLVPMPVRVNGGSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNENDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKPSPGEGDGSSEAEGGAASIQAHYKNSHLDHRHGSPMSDGNSEHSTGQSHGPPTPPTTPKTELQAGKSDGKRDGSHALREGGKPQIDFGNVDIGEISHDVMSNMETFDVNEFDQYLPPNGHAGHPSHIGGYTSSYGLTGALAAGPSAWALAKQHSQTVADSKAQVKTESSSTSHYTEQPSTSQLTYTSLGLPHYGSAFPSISRPQFDYADHQPSSSYYSHSAQASSLYSAFSYMGPPQRPLYTAISDPPSVAQSHSPTHWEQPVYTTLSRP UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.9225	Xl.1588
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		76 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SOX10	OMIM:609136 OMIM:277580 OMIM:601706 OMIM:611584
mouse		MGI	Sox10	All(14) Targeted, other(9) Radiation Induced(2) Spontaneous(2) Chemically Induced(1)
zebrafish		ZFIN	sox10	25 Lines(s)

Publications
First:		The protooncogene c-myc is an essential regulator of neural crest formation in xenopus. [Dev Cell 2003]
Most recent:		Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions. [Dev Biol 2012]
		View All Papers 21 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:
EC:
KOG:		[K] HMG-box transcription factor

Reagents		tropicalis	laevis
Clones		EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.1427.1.S1_at [+] Str.9225.1.A1_at Str.9225.2.S1_s_at	Xl.1588.1.S1_at
Affymetrix 2.0			Xl2.1588.1.S1_at

Symbol legend[+]