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Summary Expression Gene Literature (113) GO Terms (40) Nucleotides (81) Proteins (32) Interactants (1038) Wiki
XB-GENEPAGE-480303
Gene Symbol: sox10

Gene Name: SRY-box 10

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: HMG-box transcription factor

Protein Function :
Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox9 to induce neural crest progenitors. Acts downstream of wnt-signaling at the neural plate b...[+]

Interactants: Loading ...
Disease Ontology: PCWH syndrome [+]

OMIM Diseases: PERIPHERAL DEMYELINATING NEUROPATHY, CENTRAL DYSMYELINATION, WAARDENBURG SYNDROM [+]

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Xenbase Gene ID XB-GENE-480304 XB-GENE-865362 XB-GENE-17343488
Gene Symbol sox10 sox10.L sox10.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot RefSeq TrEMBL TrEMBL Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine sox10 sox10.L sox10.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SOX10 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Sox10 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR sox10 ZFIN Ensembl
chicken
GEISHA SOX10 Ensembl
fruit fly
worm
WORMBASE
Publications
First Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation., Development 2000                
Most Recent A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus., Sci Rep 2019                
All View All Papers 39 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 40 terms 12 terms 2 terms
PANTHER sox10
KEGG Pathways K09270 K09270 K09270
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
Dharmacon Dharmacon Dharmacon
Morpholino sox10 MO1 sox10 MO1 sox10 MO1
Affymetrix 1.0 StrJgi.1427.1.S1_at [+] Xl.1588.1.S1_at
Affymetrix 2.0 Xl2.1588.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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