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Summary Expression Gene Literature (3) GO Terms (26) Nucleotides (438) Proteins (39) Interactants (400) Wiki
XB-GENEPAGE-480627
Gene Symbol:
traf6

Gene Name:
TNF receptor associated factor 6

Synonyms:
xtraf6 , rnf85 , traf6-b , traf6-a ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-protein ligase

Protein Function :
E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-480628 XB-GENE-865394 XB-GENE-6254727
Gene Symbol traf6 traf6.L traf6.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493524
444777
734929
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine traf6 traf6.L traf6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TRAF6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Traf6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Traf6 Ensembl
zebrafish
ZFIN, AGR traf6 ZFIN Ensembl
chicken
GEISHA TRAF6 Ensembl
fruit fly
FLYBASE Traf6 Ensembl
Publications
First TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation., J Biol Chem 2000  
Most Recent Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation., Cell Rep 2019            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 8 terms 8 terms
PANTHER traf6
KEGG Pathways K03175 K03175 K03175
KOG [T] TNF receptor-associated factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks traf6
Antibodies Traf6 Ab1 Traf6 Ab1 Traf6 Ab1
ORFs traf6 ORF1 traf6.L ORF1 traf6.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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