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Summary Expression Gene Literature (6) GO Terms (21) Nucleotides (50) Proteins (26) Interactants (573) Wiki
XB-GENEPAGE-480764
Gene Symbol:
spry4

Gene Name:
sprouty RTK signaling antagonist 4

Synonyms:
sprouty4 , sprouty-4 , sprouty 4 ( Add synonyms , Nomenclature history )

Gene Function:
regulation of signal transduction

Protein Function :


InterPro :
RRBP1 , Rib rcpt KP , Sprouty , SPRY4 [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypogonadotropic hypogonadism [+]

OMIM:
HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA; HH7 [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-480765 XB-GENE-6486280 XB-GENE-17339261
Gene Symbol spry4 spry4.L spry4.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100498065
108710922
108713274
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein TrEMBL NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine spry4 spry4.L spry4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SPRY4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Spry4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Spry4 Ensembl
zebrafish
ZFIN, AGR spry4 ZFIN Ensembl
chicken
GEISHA SPRY4 Ensembl
fruit fly
Publications
First Regulation of Sprouty2 stability by mammalian Seven-in-Absentia homolog 2., J Cell Biochem 2007  
Most Recent Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway., Sci Rep 2020                        
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 3 terms 3 terms
PANTHER spry4
KEGG Pathways K17385 K17385 K17385
KOG [T] Signal transduction protein Enabled, contains WH1 domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks spry4
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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