Gene Symbol: dand5 [provisional] Gene Name: DAN domain family member 5, BMP antagonist [provisional] Synonyms: 51-B6, xCoco, coco, cer2, crl2, cerl2, dante, grem3, cktsf1b3 Add Xenopus synonyms Gene Function: maternal BMP/TGFbeta/Wnt inhibitor Interactants: nodal(4) , cer1(3) , nbl1(3) , nodal1(3) , gdf1(2) , gdf3(2) , lefty(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001044497|Xenopus (Silurana) tropicalis DAN domain family, member 5 (dand5), transcript variant 2, mRNA CAGCGACTCTGGGTCAGTATTGACCCTCCAGCCAGACAGACGAAAGGGGACCCACAAACCCCCAGACCCCAAACCCCTAATACGGAGAACATGCTGCTGTTCCGGGCCGCCAGCCTATTGCCCCTTCTCTGTTTCACAGTCGGGGCCTTTCCCTTTATGGATGAAGAAGGGTCGGGCTCTTTTGCCCAGGAGGTGCTACATAGCAGATCCTACCCCCTCGCTAATGCCCACCGTGGACCCTTCGTGGACCTGCCACTATTCCGACAGAACAGGAGGAAAATCTCCCAGAATTTCATCCTGCACTCGGATCCCAGGGAGCACATGGATGAGGAGGCGCTGAGGAGGAAGCTGGTGTGGGAGAGCGCCATCCGGAGGGAGAAGATGAGATCCCACCCAGACCAGGTGCTGCCCATTGGGCAAGATGCCTTGAAACGCTCTCGATGCCACGCCTTGCCTTTTATACAGAATGTGTTCAGGAAGAACTGCTTCCCGGTGCGCCTCCCTAACAAGTTCTGCTTTGGCCAGTGCAACTCCTTCTACGTGCCAGGTTGGCCAGCCGGACTCTCGCAGCCCTGCACTTCCTGCGCCCCCAGCCGATCCCGACGCATTTCACTGCCGCTACGCTGTCGCGCCGGGCACCTCGCTTGGCAGGAAGTGGAGCTCGTAGAAGAGTGCGAATGCGAAACCCGCTACGACAGGAATACCGTGGAGCCAGCTGGCAGCGGAGAGGGCTTCCTGCCCGTGTCTTAGCGCCCCAACCCCACTAAATGTGACCAAATGGACCAAACTATGTGACGCGGGGCCTCTGCGCCCCCAGAATCTTTACCCCCCCCCCCTCGACTGGCGCCCCTTTGCCAAAGCAGGGAAAGTGCCAACGACTTGACGACTTTATTTAAAATGAACAGTTCTGACCGACGGCTAATTATATACGCTTGTCTAGATTTCCCAGAATTCCTAGGGCAAGCCTGTGACCAAGCCCCCCCTTATTGGGCGGCTGTTATAGTGATTGAACATGGCGGAACTCATTGCGTTCTGCCTCTTTATTGTACCCGGGAGACTGGTCTCTCTGCCATATTGTGCCGTGTATGAGGGCTGTGCCCGTCCTACCTTCCTATTTATACAAGAGATGGTTTTATTATTAGTGTATTGTCTGTGCCAATCCGGGAGTAGCTTCCCAATATCCAGCCATTTCACTGGTTCTCTTCCTGTCCCTTAATGTAATAGGAAGTGCAGTGCAATAGCGCCCCCCCAGGTTGAAATGAACCAGGAAAGCCTGTGTTTTATGTCAAATTTTAGGGATTGGTGTGACTGGTAGGGCATGCTGGGAGATCTGCACCTACCCTAATATCCCAGTTGGAAGCTGATAGGGGTCCCGGGGCCCCTAAGTAGTTACACTACTGCAGAAAGGATTCATGCCAAGGGTTCCCAGCCAATCAGCTCCTGCCCTGGCACTTCCAAACGAACTTTCTTCAATTAAATGAGCGCAGAGACTTGTTTGTACCCTTTTTATTTATTGATGCCTGCTAGATAATTGCCCCCCCTGGTGTTCTGTCTCTTGATGCCCCTGATTGTCGGGGCTCACTGTAGCTGGGGGCGCCCATCAATATTTTACTGCCCCCCCTCCCTGTGGAGGAGAAAATGTAAATGGAAAATCCATACAAAGGCCCCCATGGTCATTTTTAATTTAATGTTTAAAGGGGAACTGACATTTAAGTGCCCCCTATGCACTTCAGCAAGGCCCCCAATGCTCCCAGTCTCCTCTTGGCATCAGACCGTAACACAAGCTTCCTGTTCTAGGGTTGCCAGCCCCCCCTTTAGTCCCGGGCACATACGAGATTCACATAGGGTATTTTTAAGATGCATTCTGCATGGCTGCACAGAAACCAGTACGTGCGGCGTGCATCTAAACGAACGGCTAATTAGCCCTGCATGTCAATTAGAACCTTGTGGCTTCCTTTATATATACCCAATAGGCATTAGGGTGTTGAAAGGAGGCAGCTGCAACTGATAACCACTTCTACTACAACTCCCAGCATCCCCTTGCAGGCATGTTGTGAGTTATAGTGTGTGTATATATAATATATATTGGCTTGATATACCCCCTGTTGGAGAATGTAAGGATACTTGAAGCCATTGAGGGGTTCCATGACCTCACCCTCTGTGACTTCTAATCCGCAGGCCTCAGGGAGTCATGTGACCAAGCAGGAGTTTAGTAACTGTGCCTCCGATGTACATAGAAGCTGTAAATATAATTTCCTACATTTTCTGCTCTGTCTCACGCCATTGTTTTTAAATAAAATACCTCTTTTTTTTACATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001098726|Xenopus laevis DAN domain family, member 5 (dand5), mRNA CAGCGACTCTGGGTCAATCTTGACCCTCCAGCCAGACGACAGGGGACCGACAAACCCCCAGACCCCAAACCCTAATAAGGAGGATTGTGTAAGAAGACATGCTGTTGTTCCAGGCCACCAGCCTATTGGCCCTTCTCTGTTTCACGGTCAGGGCATTTCCCTTTATGGAAGAAGAAGGGTCGGCTTCGTTTGCCCAGAATGTGCTCCACAGCAGATCCTTCCCAGTCTCCCACCATGGAGCTTTCATGGACCTGCCGCTATTCAGACAGAACAGGAGGAAAATATCCCAGAATTTCATCCTGCACTCAGATCCCAGAGAGCACATGGATGAGGAGGCGCTGAGGAGAAAACTGGTGTGGGAGAGCGCCATCCGCAGGGACAAGATGAGATCCCAACCAGACCAGGTGCTGCCCATTGGGCAAGATGCTCTGAAACGCTCCAGATGCCATGCCTTGCCTTTCATACAGAATGTGTTCAGGAAGAACTGCTTCCCAGTGCGCCTCCCTAACAAGTTCTGCTTTGGCCAGTGCAACTCCTTCTATGTGCCTGGTTGGCCTGCGGGACTCTCCCAGCCCTGTACGTCCTGCGCCCCCAGTCGATCCCGGCGCATTTCTCTGCCGTTACGCTGTCGTTCCGGTCACCTTGCTTGGCAAGAGGTGGAGCTGGTGGAAGAGTGCGAGTGCGAAACCCGCTACGACAGGAATACGGTGGAGCCAGCTGGCAGCGGAGAGGACTACCTGCCCGTTTCATAGGCCCAAACTGCTCTACATGTGCCCAAATGGACCAAACTATGTGACCCGGGGCCTTGGCGCTCCCAGTAACTTCACCCTTTGACAGGCGTCCCGTTGCCAAAGCAGAGGAAGTGCCAACGACTTGACGACTTTATTTAAGAATGAACAGTTCTGACCGACGGCTGATTTATACGCTTGTCTAGATTCCCAGAATCCCTAGGGGGAAAGCCTGTGACGAAGCTCCCGCTTTATTGGGAGGGTGTGAGTAATGATTCAACATGGCGGAATTCTGCCTCTTATTGTACCCGGGAGACTGGTCTCCTGCCATATTGTGCTGTGTATAAGGGCTGTGCCCGTCCTGCTCATCTTTTATACAAGTGATGCTTTTATTGGTAGTTATTATGCATTGTCTGTGCCAGTCCTGTTGTCAATTCAACTTTCCAGACCGCGTCTATAAGTGTCATGGTTATTGATGGCGTTGGTTTTGCCTTTCTGCACTGCTGGTTCTGACTCTTAAAATAATGTAGGTTCTTGTCCAGGTCAGTTGATCCGCTGGCTGCTGCATTGTTTTGGGAGTCTGAGCCAGCAGTGCAGAGAATATAAACAGACATGGCTTCCAATAGCAGTGACTTTTACCTAGAACCAGTGGAAATGAGGAATGGATATTGGGAAGTCTTATTCCTGATTTTAAGCAGAGTTGCCCTTTAACCTCTACCACATATAAACCTTCAGCTGTAATTGCTCCCCTTATTTATTTATTCCTGCTATAAAATGCCCCTCCTACAGCGATTGTTCTCAGAGAGATGCCTCTGATTGGATGGGTGCATTGTATCTAGTGTTCTGATTGGATGTGTGCACTGCATCTAGTGTTCTGATTGGATGTGTGCACTGCATCTAGTGTTCTGATTGGATGTGTGCACTGCATCTAGTGTTCTGATTGGATGGGTGCACTGTATCTAGTGTTCTGATTGGATGGAGGCACTGCATCTAGTGTTCTGATTGGATGGGTGCACTGTATCTAGTGTTCTGATTGGATGGGTGCACTGTATCTAGTGTTTTGGTTGGATGAAGGCGTTGTATCTGTGCTCTGGCACATAATGTGTTAAGTCTGGGTTACATTCAGTCACCCATTGATATTTTACAGCTCCCCCCCCCCTCGTCCCTGCAGAGAAACTTTAAACGGAAAATCTATGCAAAGGCCCCCTGGCCATTTAATTCTGTATTTAAAGGGAAACTGACTTTACTTCAGCTAGGGCCCTAGTTTGCTCTAATAAAAGCTTCCCGTTTTAGGGTTGCCAGTTCAGTCCCAGGCATGTACATGTACAAGATTCACTTAGGGCATTGATAAGATGCAAGCTGCATGGCTGCACAGAAACCAGTACGTGCTGCGTGCATCCAAATGAAACGCTAATTAGCCCTGTGTGTCAATTAGGTGCCGACCATTGTATCCCGTCCCTTCATTCCGGGTGAACCTGAACTGCTCTGTCTTGGCAACTGCTAATCACTTGTACTACAACTCCCAGCATCCCCTGGCAGGCATGTTGAGAGTCTAAGTGGGCAGTTGCTGCAGAGCCCTGGCAGATTATTGGAGAACATGAGGATGTTTGAAGCCACCAAGGAGTTCTGGGACCTTTATATAATCCTGTGACTCCTCGGTGACCGTCATTAGTCATGTGACCAACTGGGTGCCACGTGGCAAAGCCAAACCTTTTAGGAGTTCAGCAAACGTCCCTCTAATGTACATAATGTTTGTAAATATTTTTGGTACCATTTCAGATGTTTTCTGGTTTCATGCCATCTTTTTTTAAAAATTAAAATTCTCTTTTTTTACATATAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001037962|DAN domain family member 5 isoform 2 [Xenopus (Silurana) tropicalis] MLLFRAASLLPLLCFTVGAFPFMDEEGSGSFAQEVLHSRSYPLANAHRGPFVDLPLFRQNRRKISQNFILHSDPREHMDEEALRRKLVWESAIRREKMRSHPDQVLPIGQDALKRSRCHALPFIQNVFRKNCFPVRLPNKFCFGQCNSFYVPGWPAGLSQPCTSCAPSRSRRISLPLRCRAGHLAWQEVELVEECECETRYDRNTVEPAGSGEGFLPVS UniProtKB	Refseq >NP_001092196|DAN domain family member 5 precursor [Xenopus laevis] MLLFQATSLLALLCFTVRAFPFMEEEGSASFAQNVLHSRSFPVSHHGAFMDLPLFRQNRRKISQNFILHSDPREHMDEEALRRKLVWESAIRRDKMRSQPDQVLPIGQDALKRSRCHALPFIQNVFRKNCFPVRLPNKFCFGQCNSFYVPGWPAGLSQPCTSCAPSRSRRISLPLRCRSGHLAWQEVELVEECECETRYDRNTVEPAGSGEDYLPVS UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.3903 [+] Str.44988	Xl.51884
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	DAND5
mouse		MGI	Dand5	All(3) Targeted, other(3)
zebrafish

Publications
First:		Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest. [Mech Dev 2001]
Most recent:		Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos. [FASEB J 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.3903.1.S1_at [+] Str.44988.1.A1_at	Xl.25775.1.A1_at
Affymetrix 2.0			Xl2.51884.2.S2_at [+] Xl2.51884.2.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images