sox8 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (11)

Nucleotides (81)

Interactants (93)

XB-GENEPAGE-480864

Gene Symbol: sox8 Gene Name: SRY (sex determining region Y)-box 8 Add Xenopus synonyms Gene Function: HMG-box transcription factor Interactants: sox10(8) , snai2(7) , sox9(7) , pax3(6) , myod1(5) , sox2(5) , twist1(5) View All	1/3

XB-GENE-480865

XB-GENE-480869

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002932269\|PREDICTED: Xenopus (Silurana) tropicalis transcription factor Sox-8-like (LOC100497725), mRNA CAGGGAGCTGTAGTCTGGCCGCTCTGTGAGGCTTCTCCTCCCCTCATACAGTCGCCACAGCCAGGGATCTGGGCTCCCACTAATGACTGGATCCCCTTTAGGAGCTGACAAATCCAGACCCCCCCAGGACTAAGTTCATTGACTCTGGAAATCGCTGCGAGTGTTGGAGCTGTGCTGCCGCTGCGCCTCTGGACTGATCCCTCTCCGGTGATTGCGCACCCATTGCCTGTTTTACGCACGGTGCCAACCTTGCGCGCATTTTGCGCGCTGCTCCCCCTCAGCCCCAAGCCCGGCTCCTCAATGCTGAACATGAGTTCGGAGCAGGAGCACGTCCCGGAGCCCCCCTGCAGCCCCACTGGCACTGCCAGCTCCATGTCTCACGTTTCGGACTCAGACTCGGACTCCCCGCTGTCCCCGGCCGGCTCGGAGGGGCGCGGCTCCCACAGACCCCCGGGCATCTCCCAGCTCTCCAAACGGGACGGGGAAGAGACCATGGACGAGCGCTTCCCAGCGTGTATCCGAGAGGCAGTGTCCCAGGTGCTGAAGGGCTACGACTGGAGCTTGGTGCCCATGCCAGTCCGGGGCTCCGGGGGCCTCAAGGCGAAACCCCACGTCAAAAGACCAATGAACGCCTTTATGGTAGGGGCACAGGCGGCCAGAAGGAAGCTGGCAGATCAGTACCCACATTTACACAATGCTGAGCTTAGCAAGACCCTGGGCAAGCTGTGGCGTTTACTGAGTGAAAATGAAAAACGTCCCTTTGTGGAGGAAGCCGAGAGACTGAGAGTGCAGCACAAGAAAGACCATCCCGATTACAAGTACCAACCACGGCGAAGGAAGAGCGCCAAGGCGGGCCAAAGCGACTCCGACTCCGGAGCAGAGCTGGGGCTTCACGGGGGCTCCCAGATGTACAAGAGTGACTCAGGAATGGGGAGCATGGGAGAAAATCATCTGCATTCCGAGCACGCAGGTCAAAACCACGGACCTCCAACTCCTCCCACCACGCCCAAGACTGACCTCCATCATGGCGGCAAGCAAGAGTTGAAGCATGAAGGCAGGAGGATGATGGAGAGTGGGCGGCAGAACATAGATTTCAGCAATGTGGATATCAGCGAACTGAGCAGCGAAGTCATCAACAATATAGAAGCCTTTGACGTGCATGAGTTTGACCAATATCTTCCCCTTAATGGCCACGGGCCTATTCCTGCTGACCATGGGCAGAATGCAACAGCGGCACCCTATGCGTCCTCGTATACCCACGCGCCCGGAGCCACCGCAGCCCCCGTTTGGTCGCACAAGAGTCCCTCTACTTCATCTTCTTCTTCCAGTGAGTCCGGTCAACAGAGACCCCACATCAAGACAGAGCAATTGAGCCCCAGCCATTATAACGACCAGTCTCAGGGGTCACCTACCCATTCTGACTATAATACCTACAGTGCCCAGGCATGTGCCACCACCGTGCCAAGTGCTACAGTGCCCACCACTTTCCCCAGCTCCCAATGTGACTACACGGACCTCCCAAGCTCTAATTATTACAACCCATACTCCGGTTATCCATCCAGTCTCTACCAATATCCATACTTCCATTCGTCCCGGCGGCCTTATGCTACACCTATCCTCAACAGCTTGTCCATCCCACCCTCTCACAGCCCCACCTCCAACTGGGACCAGCCTGTCTACACAACCCTGACGAGGCCTTAAACGAGTTTTTTCCTTGAGTGAAGTGACTATAACGCCATAATAAGGTCTCTGGTAGCTGAACTTCTTCCAGAACATATGCACTATGACGGAGCGGTGGGAGACGCAGTGCCAGTTTCTAAGTGCCTGCTGATAAACTGAGGATTTTTTTCTTTTCTACTCTGAAACGGGGTGATGGGCCTTCGAGGCTTCCCCAGAAATGAATTTGGAAATCTATATTTTATGGGCTGTGACATAAGATGAAGGGGAATTCTCCTACATGAAGACTTTGAACAGTAGGTGCCAAAAAGCTTTGCCGTTTTATGCGACGTGAAACCAGACCAACGATTCTGATTCTGACCAATTTCTACATTTCCAACAAGTCCGTTTCCAACAAGACAAGAGGTTCGACCAATGATGTTGCCTTTGGGTTACTGTTGTAGTATTCCCTATCTGATGGCATTATCCAGCATTGCTCCCAAAACCCCAATGGCCCCCTCCCCCCCCAGTGACTGTATCTGGGCTCCGGCGAGGAATTCCTACAACTTTTCCCCTTTCTCGTGCCTCATGGTTTTTTTTGTTTGACTACGGAGAGTCCCATTTCCATGGAATTTTCTAAGCAATGTTTTAAACTGTAATTAACATTTTTTTTTTTCCTAAATGTCCTTATAGTTTTAAGAGCGGTTTAAAAAAAAAAAAAAATTATATATATATAAATATAAATATTTATGTTTCCGTATTAGAATTGTTTAATGACTTTATTTTTGGAGAAAGGCGTTGTAATTAATGGAGAGGATTCATTTTCATTTATTCCCGATATTGTGCTTCCTACATTCTTTTTTTTTTTTTCCGGAAAAAAACAACAAATTCTGTTATTTTTGATATTTAATAAGAAATCTAAAGGGCTAAAGGCAAAGTTCACATTTATTCCCCCTAAATATAAAAATATATATTGGCCTGGAATTACTGGTGAAGTGGATTTTTTCAAATGAAGGAGAATTTTTACTTTATCCAAAAATTGGAAACAAAATTAAATACAGGTATGGGACCTGTAATCCAGAATGCTCGGGACCTGGGGTTTTCCAGATAAGGGATCTTTCCGTAATTTGGATCTCCATACCTTGAGTCTACTAAAAAATTAATTGCCTCCAATAAGGATTAATTATCCCATTATCCAGAATACTCGGGACCAAGGGTATTCCGTATAAGGGGTCTTTCCGTAATTTGGATCTCCATACCTTGAGTCTACTAAAAAATTAATAAAACATTAATTTAACCAAATAGGATTGTTTTGCCCCCGATAAAGGGTAATTATATCTTAGTTGGGATCAATTACAAGGTATTATTTTATTATTATTTTATTATTACAGAGAAAAAGGAAATCAGTTTTAAAATTCTGAATTATTTGATTAAAATGGAGTCTATGGGAGCCAGGCTTTCCATAATTCAGAGCTTTCTGGATAACGGGTTTCCGGAAAAGGGATCCCATACCTGTACTGTTTTATTATTACAGAGAAAAAAGGAAATCGTTTTTAAAAATGAGAATTATTTGGGAGACGGATTTTCCGTAATTCAGAGCTTTCTGGATAACGGGTTTCCGGATAAGGGATCCCATACCTGTACTGTTTTATTATTGCAGAGAAAAAAGGAAATCGTTTTTAAAAATGAGAATTATTTGCTTATAATGAAGTCTATGGGAGACAGATTTTCCGTAATTCAGAGCTTTCTGGATAATGGGTTTCCGGATAACGGATCCCATACTGTAATGGTTATTTTTTTTTTTTTAATTGGCAGCAACAGGATAGAAGGATAGAATAAATGTGTCCTCATTGTAGAAATACTCTTAGTGAACAAAATAACCCCGAATATTCTTATTAAGCAATAAAACGTTGAAAAATGTATTTAAAGACCAAACTAATTATTTTGTGAATTTTAGCCCAATATAAATCTGCTTTTTTATAAAAAATAAAATAAAAAACATGTGACAAGGGACCAGTCTCTCCCCGGAGATCCTTAACACTAAATCCATCTCTCGATTTGTTGAAATATTTCGATTTTGACTAATATTTGTTTATTTTTTTCGTTTTATTTTTTTATTTCTCCCGTTTCATTGTATGCTGAGCATATAATAACGTCTGTTTTATCATCAACTTGTGCCTTTTTAAAAAAAATATATATATATATATTAAAAAAAAAAAAAA	Refseq >NM_001090495\|Xenopus laevis SRY (sex determining region Y)-box 8 (sox8), mRNA TCGGCACGAGGGAATCATTTGCGCATTTGTGCCAGTTACGCACTGTGCCAGCCTCGCGCGCTTCTTGCGCGTCTCTCCTCCTCAGCTTCTTCCAGCCCCGGCTCCTCAATGCTGAACATGAGTTCGGATCAGGAGCCTCCCTGCAGCCCGACTGGCACTGCCAGCTCCATGTCTCACGTTTCGGACTCAGACTCGGACTCTCCGCTGTCTCCAGCCGGATCAGAGGGGCGCGGCTCTCACCGACCCCCGGGCATCTCCAAACGGGACGGGGAAGAACCGATGGACGAGCGCTTTCCAGCTTGTATTCGAGATGCAGTGTCCCAAGTGCTGAAAGGCTACGATTGGAGCTTGGTGCCCATGCCAGTCCGGGGATCCGGGGGCCTCAAGGCTAAACCTCATGTCAAGAGACCAATGAACGCCTTTATGGTTTGGGCACAGGCAGCCAGGAGGAAACTGGCAGATCAATACCCGCATTTACACAATGCTGAGCTCAGCAAGACCCTGGGCAAACTGTGGCGTTTACTGAGTGAAAATGAAAAACGTCCCTTTGTGGAGGAGGCTGAGAGACTGAGAGTCCAGCACAAAAAAGATCACCCTGATTATAAGTACCAACCACGGCGAAGGAAGAGCGTGAAGGCAGGGCAAAGTGACTCGGACTCCGGAGCAGAGCTGGGTCATCACCCTGGATCCCAGATGTACAAGAGTGACTCAGGAATGGGGAGCATGGGAGAAAATCATCTGCATTCCGAGCATGCAGGTCAGAATCATGGACCTCCAACTCCTCCAACCACCCCTAAGACTGATCTTCACCATGGCGGCAAGCAAGAGTTGAAGCATGAAGGCAGAAGGATGATGGACAATGGGAGGCAAAACATAGATTTTAGCAATGTGGATATCAATGAACTGAGCAGTGAAGTCATCAGCAACATAGAAGCTTTCGACGTGCATGAATTTGATCAGTATCTTCCCCTTAATGGCCACGGGGCTATACCTGCTGACCATGGGCAGAATACAACAGCGGCACCTTATGGGCCCTCGTATCCTCATGCGGCTGGGGCCACACCAGCTCCTGTTTGGTCGCACAAGAGCTCCTCTACTTCCTCTTCTTCTTCCATTGAATCTGGTCAACAGAGACCCCACATCAAGACAGAGCAGCTGAGCCCCAGCCATTATAATGACCAGTCTCAGGGGTCACCTACCCATTCTGACTACAATACCTACAGTGCCCAGGCATGTGCCACCACTGTATCAAGTGCTACAGTGCCCACCGCTTTTCCAAGCTCCCAATGTGACTACACAGACCTTCCAAGCTCTAATTATTACAACCCATACTCTGGTTATCCATCCAGTCTCTATCAATATCCATACTTCCATTCATCCCGGCGGCCTTATGCTACACCCATCCTCAATAGCTTGTCCATCCCACCCTCTCACAGCCCCACCTCCAACTGGGACCAGCCTGTCTACACAACCCTGACAAGGCCTTAAATGTTTTTTTTTCCCTTGAATGAAGGACTATAATGCCATAATAAGGTCTCTGGTGGCTGAAATTCTTCCAGAACATATGCACTATGATGAACAGTGGGAGACGCAGTGCCAGTTTCTAAGTGCCTGCTGATAAACTGAGGATTTTTTCTTTTCTACTCTGAAATGTGGCGGTGGGCCCTTAAGACTTCCCCAGAAAATAATTTAGGCAAATCAAATTGGAAAGCTATATTTTATTTTTTATGGGCTGTGATGTGACATAAGATGAAGGATAAACCTCCTGCATGAGGACTTTGAACAGTAGGTGCCAAAAACCTTTGACATTTTATGCAACGGGAAACCAGACCAACAATTCTGATTCTTCTCTGACCAACTTATACATTTCCAAAAAGTCTGTTTGAGTGTGTCCGTGAAAAGCAAGAGGGTCAACCAATGATGTTCCCTTTGGGTTACTTT
Protein		NCBI Protein >XP_002932315\|PREDICTED: transcription factor Sox-8-like [Xenopus (Silurana) tropicalis] MLNMSSEQEHVPEPPCSPTGTASSMSHVSDSDSDSPLSPAGSEGRGSHRPPGISQLSKRDGEETMDERFPACIREAVSQVLKGYDWSLVPMPVRGSGGLKAKPHVKRPMNAFMVGAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGQSDSDSGAELGLHGGSQMYKSDSGMGSMGENHLHSEHAGQNHGPPTPPTTPKTDLHHGGKQELKHEGRRMMESGRQNIDFSNVDISELSSEVINNIEAFDVHEFDQYLPLNGHGPIPADHGQNATAAPYASSYTHAPGATAAPVWSHKSPSTSSSSSSESGQQRPHIKTEQLSPSHYNDQSQGSPTHSDYNTYSAQACATTVPSATVPTTFPSSQCDYTDLPSSNYYNPYSGYPSSLYQYPYFHSSRRPYATPILNSLSIPPSHSPTSNWDQPVYTTLTRP	Refseq >NP_001083964\|transcription factor Sox-8 [Xenopus laevis] MLNMSSDQEPPCSPTGTASSMSHVSDSDSDSPLSPAGSEGRGSHRPPGISKRDGEEPMDERFPACIRDAVSQVLKGYDWSLVPMPVRGSGGLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKAGQSDSDSGAELGHHPGSQMYKSDSGMGSMGENHLHSEHAGQNHGPPTPPTTPKTDLHHGGKQELKHEGRRMMDNGRQNIDFSNVDINELSSEVISNIEAFDVHEFDQYLPLNGHGAIPADHGQNTTAAPYGPSYPHAAGATPAPVWSHKSSSTSSSSSIESGQQRPHIKTEQLSPSHYNDQSQGSPTHSDYNTYSAQACATTVSSATVPTAFPSSQCDYTDLPSSNYYNPYSGYPSSLYQYPYFHSSRRPYATPILNSLSIPPSHSPTSNWDQPVYTTLTRP UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		[+] Str.67240	Xl.29789
Unigene EST Profile			EST Profile
GEO data			GEO
Images		24 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SOX8
mouse		MGI	Sox8	All(4) Targeted, other(3) Targeted, knock Out(1)
zebrafish		ZFIN	sox8	10 Lines(s)

Publications
First:		Functional analysis of Sox8 during neural crest development in Xenopus. [Development 2006]
Most recent:		The LIM adaptor protein LMO4 is an essential regulator of neural crest development. [Dev Biol 2012]
		View All Papers 6 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:
EC:
KOG:		[K] HMG-box transcription factor

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0
Affymetrix 2.0			Xl2.29789.1.S1_at [+] Xl2.53219.3.A1_at Xl2.53219.3.A1_s_at

Symbol legend[+]