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Summary Expression Gene Literature (29) GO Terms (23) Nucleotides (42) Proteins (23) Interactants (390) Wiki
XB-GENEPAGE-480901
Gene Symbol:
dll4

Gene Name:
delta-like 4

Synonyms:
delta 2 ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction/notch signaling pathway

Protein Function :
Putative Notch ligand involved in the mediation of Notch signaling.



Interactants:
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Diseases: 


Disease Ontology:
Adams-Oliver syndrome

OMIM:
ADAMS-OLIVER SYNDROME 6; AOS6

External Links:
1/2
 
Xenbase Gene ID XB-GENE-480902 XB-GENE-6489047 XB-GENE-17344831
Gene Symbol dll4 dll4.L dll4.S
Chromosome Chr8 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100489166
108699270
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein Uniprot NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dll4 dll4.L dll4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards DLL4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dll4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dll4 Ensembl
zebrafish
ZFIN, AGR dll4 ZFIN Ensembl
chicken
GEISHA DLL4 Ensembl
fruit fly
Publications
First Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals., Development 1993            
Most Recent Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling., Dev Cell 2021    
All View All Papers 6 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 4 terms 0 term
PANTHER dll4
KEGG Pathways K06051 K06051
KOG [T] Fibrillins and related proteins containing Ca2+-binding EGF-like domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dll4
Clones EXRC Horizon Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info