srsf2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (6)

Nucleotides (2808)

Interactants (14)

XB-GENEPAGE-481124

Gene Symbol: srsf2 Gene Name: serine/arginine-rich splicing factor 2 Synonyms: sc35, pr264, sc-35, sfrs2, sfrs2a, srp30b Add Xenopus synonyms Gene Function: nucleic acid binding Interactants: coil(1) , eif3a(1) , gadd45a(1) , hnrnpc(1) , hnrpdl(1) , il1r1(1) , myc(1) View All

XB-GENE-481125

XB-GENE-481129

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203997\|Xenopus (Silurana) tropicalis serine/arginine-rich splicing factor 2 (srsf2), mRNA CGCTGGCTTAGTCCTATTGCAGGGCTGAGCGCTCGACAGTGGCTGCTGTTTCTCTGCATCGTGTGTGAGTGGGCCCAGGTTTCGTTTTGTGTCGGCGTTGCTTTCCCACTTAAGTCGCGATTCCATGAGCTACGGTCGGCCTCCGCCTGACGTGGAGGGAATGACCTCTCTCAAGGTTGATAACCTAACGTACCGAACCTCCCCGGAGACCCTGCGCCGGGTGTTCGAGAAGTATGGCAGGGTGGGCGACGTGTACATCCCCCGGGACCGATACACCAAGGAGAGCCGGGGCTTCGCCTTCGTTCGCTTCCACGACAAGCGCGATGCCGAAGACGCGATGGACGCCATGGATGGGGCCGTGCTGGACGGGCGGGAGCTGAGGGTGCAGATGGCCCGGTACGGCCGGCCTCCCGATTCCCACCACGGAAGGAGAGGGCCCCCTCCTCGCAGATACGGCGACTACGGCCGGCGGAGCAGAAGCCCCAGGAGGCGACGTCGCAGCCGTTCCAGAAGCAAGAGCAGGTCAAGGTCCCGCAGCAGGTCTCGCTACAGCCGCTCAAAGTCCCGCTCTCGCACAAGGTCCCGCACCCGGTCCAGCTCAAAGTCTCGCTCGGCAAGGAGATCCAAGTCTAAGTCATCGTCCGCGTCCAGGTCTCGCTCCCGCTCCAGATCTAGGTCCAGAACAAGAAATTCGCCGCCGCCTCCACAGAACTCCAACTCCAAATCCAGATCCCGCTCCCAGAGCCCTCCTAAGTCGCCAGAGGAAGAGGGCGCCGTGTCTTCCTGAAGAGTCAACAGCCGGAATTCTACAAGCTGGACAACATCCCTGGGGTGATAATTCATTCATTAGCTCATCAGCCCATGGAGAAACACAGAGCAAAGCAATGGCCTGCCGAAAAGGTGGTTATTTGTATGATTTCTTAAAACTTTTTACCTGTTTTCAGTTGCGCTTCGTGTCGCAAGACTTTATACATTTTATGTGCAATTTTGTTCCCTGTTATTCCGATTTCTTGTAATTTAGTGAAATGACCGACTACAGATTTCAATATTGGCTTGGATGTTTGAGGTAACTTGCTTTTGTCAAAGTATCATTGAAATTCTGTGGGGGAATGAAGGTTATCTCACAGCTAGTATGCTCCACAGCCCTACTTATAGTGCATGGGCGCTGTGCCTCGTCAGATTGACCGGCCAGGGTTCCACCCAGTCATATGTTCTTGTAATACGTGAGCCTTGAAGTGTGGGGGTAAAAAATGTTCATGTGACAATGTTGCAAGGGAGTGTTTTTGTTTGATTACAACTCTAATTTCTTCTCTTGTGTATTTTTGTGCACTAGGCGCAGTTGTGTAGCAGTTGTATTGCTGGTTAGCTGTTTAAGGTGGCGTGTTGCAGTGCAGAGTGCTTGGCTGTTTCCTGTTATCTCCTGATTGCTCCTGTGCTGCCTTGTCGTGCAGAAAACACAATGGCTGTCCAGTTTATTAGGATGCCTGACGACAACTGCACATCCAGTCGCCCGGGCCTTGCATATAATAACGGAGCATACAGTGAGCACATCTAGCTGATGAGAAACACCTTTATGTTTTAAACCTGGTAAATCCTGAGCATCATTGTGTGATAATATCCCATGCTGGTGTCATTCCTTTGTATGTACTGATCTGCATATCTCTGGCTCTCATTCTCTACTATAACCACTGTTTCTGTAGTAAATAAACTTTTTTTTTTCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001087274\|Xenopus laevis serine/arginine-rich splicing factor 2 (srsf2), mRNA TGGGCTGAGCTCCCGGCAGCGCTGGATGTTTTCTCTATCTGTCGTGCGTGGCTCCAGCTTTCGATTTGTGTCGGTGCTTATTACCCCACTTTACTGAAGATTCCATGAGCTACGGTCGGCCTCCGCCTGACGTGGAGGGAATGACCTCTCTCAAAGTTGATAACTTAACCTACCGAACCTCCCCGGAGACACTGCGCCGGGTGTTCGAGAAATACGGCAGGGTCGGCGATGTCTACATCCCAAGGGACCGCTACACTAAAGAGAGCCGGGGCTTCGCCTTCGTTCGCTTTCACGACAAGCGCGATGCCGAGGACGCGATGGACGCTATGGACGGGGCCGTGTTAGACGGGCGGGAGCTGAGGGTGCAGATGGCCCGCTACGGACGGCCGCCCGATTCCCATCACGGAAGGAGAGGACCTGCTCCTCGCAGATACGGCGACTACGGCCGGCGGAGTAGAAGTCCTAGGAGGCGTCGTCGCAGCCGTTCCAGGAGCAAGAGTAGGTCAAGGTCCCGTAGCAGGTCTCGCCACAGCCGCTCAAAGTCTCACTCTCGTACAAGGTCTCGTACTCGGTCCAGATCAAAGTCTCGCTCCGCAAGAAGATCTAAGTCAAAGTCATCGTCTGTGTCAAGGTCTCGCTCCAGATCTAGATCCAGAACAAGGAACTCGCCTCCTCCGCAGAACTCCAAATCAAGATCCCGCTCTAAGAGCCCTCCAAAATCCCCAGAGGAAGAGGGAGCAGTGTCTTCATGAAGAGTCAACACCTGGAATTCTACGAGATGGGACATCATCTTTTGGGTGATATCATTCATATGCCGTTCAACCCACTGAGAAATAGAGCAAAGCAACAGCCTGCCGAAAAGGTGGTTATTTGTATGATTTCTTAAACTTTTTACCTGTTTCAGTTGCGCTTCTTGCCGCAAGACTTTACATTTTCTGTGCAATTTTGTTCCTGTTCCAATTTCTTGTAATTTAGTGAAATGACCGACTACAGATTTCAATATTGGCTTGGATATTTGAGGTAATTTGCTTTTGTTAAAAGTATCATTGGAAATCAAGGTCTCACAGCTGTTATGCTCCACATCTGTGTATAGCGCATGAACACTGGGCCTCATCTGACCGGCCAGGGTTCCTCCAAGTGAAATGTTCTTGTAATGCGTGGAACTTTAAATGAAATGTACATGTAACAATATTGCAAGGGAGTGTTTTTGTTTGATTACAACTCTAATTTCTTCTCTTGTGTATTTTTGTGCACTAGGCGCAGTTGTGTAGCAGTTGTATTGCTGGTTAGCTGTATAAGGTGGCGTGTTGCAGTGCAGAGTGCTTGGCTGTTTCCTGTATCTCCTCATTGCTCCTGTGTAACGCTGCCTTGTCGTGCAGAAAACACATGGCTGTCCAGTTTATTAGGATGCCTGACGACAACTGCAAAATCCAGTCGCCCGGGCCTTGCATAAAATAACGGAGCATACAGTGAGCACATCTAGCTGATGAGAAACACCTTATGTTTTAAACCTGGTAAATCCTGAGCATCGTTTTGTAATATCACGCTGGTGTCATTCCTTTGTATGTAATGAACTGCATATATCTCTGGCTCTCACATTCTGTACTATAACCACTGTTTCTGTAGTTAATAAACTTTTTTTTTCTTTAAAAAAAAAAAAAAA
Protein		Refseq >NP_989328\|splicing factor, arginine/serine-rich 2 [Xenopus (Silurana) tropicalis] MSYGRPPPDVEGMTSLKVDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHGRRGPPPRRYGDYGRRSRSPRRRRRSRSRSKSRSRSRSRSRYSRSKSRSRTRSRTRSSSKSRSARRSKSKSSSASRSRSRSRSRSRTRNSPPPPQNSNSKSRSRSQSPPKSPEEEGAVSS	Refseq >NP_001080743\|serine/arginine-rich splicing factor 2 [Xenopus laevis] MSYGRPPPDVEGMTSLKVDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHGRRGPAPRRYGDYGRRSRSPRRRRRSRSRSKSRSRSRSRSRHSRSKSHSRTRSRTRSRSKSRSARRSKSKSSSVSRSRSRSRSRTRNSPPPQNSKSRSRSKSPPKSPEEEGAVSS

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.8693 [+] Str.4751 Str.11559 Str.47210 Str.75978	[+] Xl.4618 Xl.83314 Xl.83369 Xl.32641 Xl.33563
Unigene EST Profile		EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SRSF2
mouse		MGI	Srsf2	All(2) Targeted, knock Out(1) Targeted, other(1)
zebrafish		ZFIN	srsf2a	1 Lines(s)

Publications
First:		Small nuclear ribonucleoproteins and heterogeneous nuclear ribonucleoproteins in the amphibian germinal vesicle: loops, spheres, and snurposomes. [J Cell Biol 1991]
Most recent:		Gadd45a is an RNA binding protein and is localized in nuclear speckles. [PLoS One 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		nucleic acid binding
Biological:
Cellular Component:
EC:
KOG:		[A] Predicted splicing factor, SR protein superfamily

Reagents		tropicalis	laevis
Clones		open biosystems
		geneservice/RZPD imagenes
Affymetrix 1.0		Str.3492.5.A1_a_at [+] Str.6900.3.A1_at Str.47210.1.A1_at Str.11559.1.A1_at Str.4751.1.A1_at Str.4751.1.A1_x_at	Xl.4618.1.S1_a_at [+] Xl.23402.1.S1_at
Affymetrix 2.0			Xl2.33563.1.S1_at [+] Xl2.32641.1.A1_at Xl2.51136.2.A1_at Xl2.51136.1.S1_at Xl2.4618.3.S1_a_at

Symbol legend[+]