Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (93) GO Terms (14) Nucleotides (146) Proteins (27) Interactants (1190) Wiki
XB-GENEPAGE-481352
Gene Symbol: frzb

Gene Name: frizzled related protein

Synonyms: Frzb-1 , xfrzb , fre , os1 , fzrb , fiz , frp-3 , frzb1 , sfrp3 , srfp3 , frzb-pen ( Add synonyms , Nomenclature history )

Gene Function: secreted wnt antagonist

Protein Function :

Interactants: Loading ...
Diseases:  OMIM: OSTEOARTHRITIS SUSCEPTIBILITY 1; OS1

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/9
 
Xenbase Gene ID XB-GENE-481353 XB-GENE-17332603 XB-GENE-865117
Gene Symbol frzb frzb.L frzb.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448021
399085
734982
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine frzb frzb.L frzb.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FRZB OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Frzb MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR frzb ZFIN Ensembl
chicken
GEISHA FRZB Ensembl
fruit fly
worm
WORMBASE
Publications
First FTZ-F1-related orphan receptors in Xenopus laevis: transcriptional regulators differentially expressed during early embryogenesis., Mol Cell Biol 1994  
Most Recent The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Elife 2020                                                          
All View All Papers 14 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 0 term 4 terms
PANTHER frzb
KEGG Pathways
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks frzb
Morpholinos frzb MO1 frzb MO1 frzb MO1
ORFs frzb ORF1 frzb ORF1 frzb.S ORF1
Clones EXRC Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.0


Major funding for Xenbase is provided by grant P41 HD064556