Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (242) GO Terms (18) Nucleotides (166) Proteins (33) Interactants (814) Wiki
XB-GENEPAGE-481418
Gene Symbol:
gdf1

Gene Name:
growth differentiation factor 1

Synonyms:
vg1 , vg-1 , dvr1 , dvr-1 , gdf-1 ( Add synonyms , Nomenclature history )

Gene Function:
tgf-beta related peptide growth factor

Protein Function :
Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment.


InterPro :
ARM-like , ARMC7 , ARM-type fold , TGF-b propeptide [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
double outlet right ventricle [+]

OMIM:
CONOTRUNCAL HEART MALFORMATIONS; CTHM [+]

External Links:
1/4
 
Xenbase Gene ID XB-GENE-481419 XB-GENE-17335633 XB-GENE-481423
Gene Symbol gdf1 gdf1.L gdf1.S
Chromosome Chr01 chr1L Scaffold21
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 549573
677862
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gdf1 gdf1.L gdf1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GDF1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gdf1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gdf1 Ensembl
zebrafish
chicken
GEISHA GDF3 Ensembl
fruit fly
worm
Publications
First Identification and cloning of localized maternal RNAs from Xenopus eggs., Cell 1985  
Most Recent ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development., J Cell Biol 2019                    
All View All Papers 12 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 3 terms 3 terms
PANTHER gdf1
KEGG Pathways K05495 K05495
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gdf1
Mutants Xtr.gdf1emHorb
Morpholinos gdf1 MO1 gdf1 MO1 gdf1 MO1
ORFs gdf1.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556