Gene Symbol: ptgds Gene Name: prostaglandin D2 synthase 21kDa (brain) Synonyms: lpgds, pds, pgd2, pgds, pgds2, l-pgds, cerebrin-28, cpl-1, XlCpl1 Add Xenopus synonyms Gene Function: prostaglandin metabolic protein Interactants: slc26a4(10) , ctsl1(5) , celf3(3) , cyp26a1(2) , foxg1(2) , myod1(2) , nog(2) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 4.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001078777|Xenopus (Silurana) tropicalis complement component 8, gamma polypeptide, gene 2 (c8g.2), mRNA CATCAGCAGCCAATCACCATGAGGATTCTGCTGGCTCTCAGCTTGGTGGCCATTTGCTGCAGCCTGTGGGTCGGGGCCGAGGTTCTGATCCAACCGGATTTCCAAAAGGAAAAGGTCCTGGGCAAGTGGTACGGGATTGGCTTGGCCTCCAATTCCAACTGGTTCCAGGGCAAGAAGAACCACATGAAGATGTGCACCACCATCATCACTCCCACCGCCGACGGGAACATGGAGGTCACAGCCACTTTTCCCAAGATGGATCGCTGTGAGAAGAAGACCATGACCTACATAAAGACGGAGCAGCCCGGCCGTTTCCGCGCTAAAAGCCCCCGCTACGGCAGTGAGCACGACATGCGCGTCGTGGAAACCAACTATGATGAATTCATTCTAATGTACACGCTGAAGACCAAGGGACCAGAAACCAATCAAATTGTCTCTCTCTTTGCCAGAGACAAGGATGTGAGGCCCGAACTGCTGGATAAGTTCCAGAGCTTCGCTAAGGCTCAAGGGCTCACCGACGAGAATATTCTCATCCTGCCCCATACTGATCAGTGCATGACAGAGGCTTAGAGACTCGGGAATGCGCCGTGGCTCCAACGTGTGGCCCCCCAGTTACTCCCGTGGGTTTAGAGATTTCTTCTAATGTTTGTGGAAGCGAATCAATAAATGTTTGCATTAATCAAAAAAAAAAAAAAA	Refseq >NM_001092825|Xenopus laevis prostaglandin D2 synthase 21kDa (brain) (ptgds-a), mRNA GCAGCAGCAGCAGAGTGCGAGGTCCCAGCAAATCATGATGAGGATTTTGCTTGCTCTGAGCTTGGGGGTTGCTTGCTGCAGTTTGTGGGTCGGGGCAGAGGTGCCGCTGCAGCCTGATTTCCAGAATGAAAAGGTCTTAGGCAAGTGGTATGGCATCGGCCTGGCCTCCAACTCCAACTGGTTCAAGGACAGGAAGAGCCACATGAAGATGTGCACCACCATCATCACTCCCACCACCGATGGGAACATGGACGTCACAGCCACTTATCCCAAGATGGATCGCTGTGAGACAAAGTCCATGACTTATTTTAAGACGGAGCAGCCGGGCCGTTTCCGCGCTAAAAGCCCCCGCTACGGCAGTGAACATGACATGCGGGTAGTGGAGACCAACTATGATGAATACATTCTAATGTACACAGTGAAGACCAAGGGATCAGAAACCAACCAAATTGTCTCTCTCTTTGGCAGAGACAAGGATGTGAGGCCAGAACTGCTGGATAAGTTCCAGAGCTTCGCTAAGACTCAAGGACTCACTGATGATAATATTCTCCTTCTGCCCCACACGGATCAGTGCATGACAGAAGCTTAGAGGCTGGGGATTTCACACGTGTCGTGTCATATGTGCCCCCCCATGTACCCCAATGGGTTTAGAAAATGCTTGTGGATATGAATCAATAAATGTTTGTATTAATCACTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA		Refseq >NM_001088044|Xenopus laevis prostaglandin D2 synthase 21kDa (brain) (ptgds-b), mRNA ATGTTTGCACTGATCAGTGTGGGGCAGGATGATAATATTATCATCAGCGAGTCCTTGAGACTTAGCAAAGTTCTGGAACTTATACAGCAATTGCAGCATCAGCAGCCAATCATGATGAGGATTCTGCTTGCTCTGAGTTTGGGGGTCGCTTGCTGCAGCCTGTGGGTCGGGGCTGAGGTGCAGGTGCAGCCGGATTTCCAGAAGGAGAAGGTCTTAGGCAAGTGGTACGGCATCGGCCTGGCCTCCAATTCCAACTGGTTCAAGGACAGGAAGAGCCACATGAAGATGTGCACCACCATCATCACTCCCACCGCTGATGGGAACTTGGAGGTCACAGCTACTTATCCCAAGATGGATCGCTGTGAGACAAAGTCAATGACTTATTTCAAGACGGAGCAGCTTGGCGGTTTCCGCGCTAAAAGCCCCCGCTACGGCAGTGAACACGACATGCGGGTAGTGGAGACCAACTATGATGAATACATTCTAATGTACACAGTGAAGACCAAGGGATCAGAAACCAACCAAATCGTCTCTCTTTTTGGCAGAGACAAGGATCTGAGGCCAGAACTGCTGGATAAGTTCCAGAACTTTGCTAAGTCTCAAGGACTCGCTGATGATAATATTATCATCCTGCCCCACACTGATCAGTGCATGACAGAAGCTTAGAGGGTCGACTCTTATATGTGGCCCCTCGTGTACCCCAATGGGTTTAGAAAGCTCTTCTAATGCTTATGGAAGTGAATCAATAAATGTTTGCATTAATC
Protein		Refseq >NP_001072245|complement component 8, gamma polypeptide, gene 2 precursor [Xenopus (Silurana) tropicalis] MRILLALSLVAICCSLWVGAEVLIQPDFQKEKVLGKWYGIGLASNSNWFQGKKNHMKMCTTIITPTADGNMEVTATFPKMDRCEKKTMTYIKTEQPGRFRAKSPRYGSEHDMRVVETNYDEFILMYTLKTKGPETNQIVSLFARDKDVRPELLDKFQSFAKAQGLTDENILILPHTDQCMTEA	Refseq >NP_001086294|prostaglandin D2 synthase 21kDa (brain) precursor [Xenopus laevis] MMRILLALSLGVACCSLWVGAEVPLQPDFQNEKVLGKWYGIGLASNSNWFKDRKSHMKMCTTIITPTTDGNMDVTATYPKMDRCETKSMTYFKTEQPGRFRAKSPRYGSEHDMRVVETNYDEYILMYTVKTKGSETNQIVSLFGRDKDVRPELLDKFQSFAKTQGLTDDNILLLPHTDQCMTEA		Refseq >NP_001081513|prostaglandin D2 synthase, brain precursor [Xenopus laevis] MMRILLALSLGVACCSLWVGAEVQVQPDFQKEKVLGKWYGIGLASNSNWFKDRKSHMKMCTTIITPTADGNLEVTATYPKMDRCETKSMTYFKTEQLGGFRAKSPRYGSEHDMRVVETNYDEYILMYTVKTKGSETNQIVSLFGRDKDLRPELLDKFQNFAKSQGLADDNIIILPHTDQCMTEA

Genomic		tropicalis
Genome Browser		Xenbase JGI Ensembl UCSC			Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.53965 [+] Str.41812	Xl.74128		Xl.194
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	PTGDS
mouse		MGI	Ptgds	All(6) Targeted, knock Out(3) Targeted, other(3)
zebrafish		ZFIN	ptgdsb

Publications
First:		Membrane currents elicited by prostaglandins, atrial natriuretic factor and oxytocin in follicle-enclosed Xenopus oocytes. [J Physiol 1989]
Most recent:		Distinct and novel SLC26A4/Pendrin mutations in Chinese and U.S. patients with nonsyndromic hearing loss. [Physiol Genomics 2009]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		prostaglandin-D synthase activity transporter activity
Biological:		prostaglandin metabolic process transport
Cellular Component:
EC:		prostaglandin-D synthase
KOG:

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.41812.1.A1_x_at [+] Str.21860.1.S1_at			Xl.194.1.S1_at
Affymetrix 2.0			Xl2.47287.1.S1_at		Xl2.194.1.S1_at [+] Xl2.17730.1.A1_at

Symbol legend[+]

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