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Summary Expression Gene Literature (37) GO Terms (11) Nucleotides (144) Proteins (35) Interactants (818) Wiki
XB-GENEPAGE-481765
Gene Symbol: tle4

Gene Name: transducin like enhancer of split 4

Synonyms: XGrg-4 , XTCF-4 , groucho-related gene 4 , Xgrg4 , grg4 , esg4 , Xtle4 , gro , Grg-4 , X-groucho ( Add synonyms , Nomenclature history )

Gene Function: transcriptional regulator

Protein Function :
Transcriptional corepressor. Functions with ripply2.2/bowline to down regulate transcription of tbx6-dependent gene expression. Represses transcription of siamois and nodal3.


Interactants: Loading ...
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Xenbase Gene ID XB-GENE-481766 XB-GENE-17334468 XB-GENE-481770
Gene Symbol tle4 tle4.L tle4.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 100101787
Entrez Gene: 399397
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL TrEMBL RefSeq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tle4 tle4.L tle4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TLE4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tle4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
GEISHA TLE4 Ensembl
fruit fly
worm
WORMBASE
Publications
First Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri., J Biol Chem 1993  
Most Recent High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Dev Biol 2017                    
All View All Papers 9 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 8 terms
PANTHER tle4
KEGG Pathways
KOG [B] Transducin-like enhancer of split protein (contains WD40 repeats)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon
Antibody Tle1 Ab1 Tle1 Ab1 Tle1 Ab1
Morpholino tle4 MO1 tle4 MO1 tle4 MO1
ORF tle4.S ORF1
Affymetrix 1.0 Str.27571.1.S1_s_at [+] Xl.15157.1.S1_at
Affymetrix 2.0 Xl2.46316.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.2


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