|
XB-GENEPAGE-481765
Gene Symbol:
tle4
Gene Name: transducin like enhancer of split 4
Synonyms:
XGrg-4
,
XTCF-4
,
groucho-related gene 4
,
Xgrg4
,
grg4
,
esg4
,
Xtle4
,
gro
,
Grg-4
,
X-groucho
( Gene Function: transcriptional regulator Protein Function
![]()
Transcriptional corepressor. Functions with ripply2.2/bowline to down regulate transcription of tbx6-dependent gene expression. Represses transcription of siamois and nodal3.
Interactants:
Loading ...
Diseases: External Links:
|
|
Xenbase Gene ID
![]() |
XB-GENE-481766 | XB-GENE-17334468 | XB-GENE-481770 | |||||
Gene Symbol | tle4 | tle4.L | tle4.S | Chromosome | Chr1 | chr1L | chr1S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.1
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
||||||
Entrez Gene |
100101787
|
399397
|
||||||
mRNA |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
||||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
||||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
|
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | tle4 | tle4.L | tle4.S | |||||
Orthology ![]() |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
Publications | ||||||||
First |
Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri., J Biol Chem 1993 |
|||||||
Most Recent |
Barhl2 maintains T cell factors as repressors and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation., Development 2019 ![]() |
|||||||
All | View All Papers 9 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 16 terms | 0 term | 8 terms | |||||
PANTHER | tle4 | |||||||
KEGG Pathways | ||||||||
KOG |
[B] Transducin-like enhancer of split protein (contains WD40 repeats)
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | tle4 | |||||||
Antibodies | Tle1 Ab1 | Tle1 Ab1 | Tle1 Ab1 | |||||
Morpholinos | tle4 MO1 | tle4 MO1 | ||||||
ORFs | tle4.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



