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Summary Expression Phenotypes Gene Literature (122) GO Terms (126) Nucleotides (156) Proteins (52) Interactants (642) Wiki
XB-GENEPAGE-481819
???displayGene.symbol???:
 lrp6

???displayGene.name???: 
LDL receptor related protein 6

???displayGene.synonyms???
adcad2 , LOC108712563 , lrp6-a , lrp6-b , Xlrp6 [-] ( Nomenclature history )

???displayGene.geneFunction???
signal transduction

Protein Function :
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.


InterPro :
LDLR classB rpt, LDL receptor-like sf, LDLR class-A CS, EGF-like dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
tooth agenesis [+]

MIM:
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT 2; ADCAD2 [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info