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XB-GENEPAGE-481819
Gene Symbol:
lrp6
Gene Name: LDL receptor related protein 6
Synonyms:
Xlrp6
,
adcad2
,
lrp6-a
,
lrp6-b
( Gene Function: signal transduction Protein Function
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Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
Interactants:
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Diseases: Disease Ontology:
tooth agenesis
OMIM:
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT 2; ADCAD2
External Links:
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Xenbase Gene ID | XB-GENE-481820 | XB-GENE-6252411 | XB-GENE-865490 | |||||
Gene Symbol | lrp6 | lrp6.L | lrp6.S | Chromosome | Chr3 | Scaffold31 | Scaffold16589 | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100489328
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373826
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378494
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | lrp6 | lrp6.L | lrp6.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
LDL-receptor-related proteins in Wnt signal transduction., Nature 2000 |
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Most Recent |
Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis., MicroPubl Biol 2021 ![]() |
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All | View All Papers 17 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 50 terms | 0 term | 8 terms | |||||
PANTHER | lrp6 | |||||||
KEGG Pathways | K03068 | K03068 | ||||||
KOG |
[T] Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | lrp6 | |||||||
Antibodies | Lrp6 Ab1 , Lrp6 Ab2 | Lrp6 Ab1 , Lrp6 Ab2 | Lrp6 Ab1 , Lrp6 Ab2 | |||||
Morpholinos (on-target & off-target) | lrp6 MO2 , lrp6 MO1 | lrp6 MO1 | lrp6 MO1 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



