bmp2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (108)

Nucleotides (106)

Interactants (351)

XB-GENEPAGE-481828

Gene Symbol: bmp2 Gene Name: bone morphogenetic protein 2 Synonyms: BMP-2, xBMP-2, xbmp2 Add Xenopus synonyms Gene Function: TGF-beta related peptide growth factor Interactants: bmp4(60) , tgfb1(28) , chrd(23) , nog(22) , smad1(19) , bmp7.1(14) , ventx2.2(11) View All	1/4

XB-GENE-481829

XB-GENE-481833

XB-GENE-6252323

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001015963\|Xenopus (Silurana) tropicalis bone morphogenetic protein 2 (bmp2), mRNA TGCAGCCCAACTGCCTCTTACAGCCGGGATACAGGGAAAGGTCGCTCCTCTGCGCATCCCACTCCAGCGCTGCCTCCTTGTCCCATTCAGCGCTAATGCCTGCGGCTGCGCTGCGCTGCTATTTGCACAGGAGATCGCAGTGACATCCCGGTGCGACTCAGACCGACTCCAGTCGGGGGAGGATAACTTGGTGCTACATTGGGGCGTTCTTGGTTAAGGGACACACGATCAGTCGCACCGAGTATGTGCAAAAAGAGAAGGACTGGGCTGCGACTAGACGCGCAGATTTGCCTAATAGCCCTGGGAAGGAGAAGTTTGGAGTAAAAAGAGTCAAGTGATGTGGAAAAAACACACGGAGAGCAGAAAACCATCATCGAGACACAAACTCGGCGCACAGGTCGACAATGGTAGCTGGGATCCACTCTCTGCTCCTGCTGCTGTTTTACCAGATTTTGCTGAGTGGCTGCACCGGACTTATACCAGAGGAAGGCAAGCGGAAGTACACGGAATCTGGTCGCTCGTCTCCGCAGCACTCCCAGAGTGTACTCAACCAGTTCGAGCTCCGGCTGCTCAATATGTTTGGCTTAAAGAGGCGTCCAACGCCTGGCAAAAACATTGTGATCCCACCCTACATGCTGGACTTGTACCACCTGCATTCAGGTCAGCTGGCTGCTGATCAAGACAGTTCCCCCATGGACTACCAGATAGAGCGTGCAGCTAGCCGAGCAAACACCGTTAGGAGCTTTCACCATGAAGAATCCATGGAAGAAATTCCCGAGTCTGGCGAGAAAACAATCCAACGATTCTTCTTCAACCTTTCTTCAGTTCCGAACGAGGAGCTGGTCACTTCTGCCGAGCTACGGATTTTTCGAGAGGGGGTCCAGGAGCCATTTGAGGGTGACAGCAGCAAACTTCATCGGATTAATATTTATGATATTGTCAAGCCAGCAGCGGCTGCCTCCCGGGGCCCCGTTGTAAGACTATTGGACACCAGACTGATACATCATAACGAAAGCAAATGGGAAAGTTTTGATGTGACACCGGCAATTACACGGTGGATTGCACATAAACAGCCGAACCATGGGTTTGTTGTTGAAGTGACTCACTTGGACAATGACAAAAATGTGCCGAAGAAGCATGTGAGGATTAGCAGGTCTTTAGTCCCAGATAAAGATAGCTGGCCTCGGATACGGCCGTTGTTGGTGACTTTTAGCCACGACGGCAAAGGACATGCGCTTCACAAAAGAGAAAAGCGCCAAGCAAGGCACAAACAACGGAAACGCCTTAAATCGAGCTGCAGGAGGCATCCGTTGTATGTCGATTTCAGCGACGTTGGTTGGAATGACTGGATTGTTGCCCCACCGGGGTATCATGCCTTTTACTGCCACGGGGAATGCCCTTTCCCACTGGCAGACCATTTAAACTCTACAAACCACGCTATCGTGCAGACTTTGGTGAATAACGTCAACCCAAACATCCCCAAAGCTTGCTGTGTACCCACAGAACTCAGCGCCATCTCCATGCTCTACCTGGACGAGAACGAAAAAGTAGTATTAAAAAATTATCAGGACATGGTGGTGGAGGGGTGCGGCTGCCGTTAGGAAGGGTACACGCCGGCCGGCGGCGAGACAGAAAGCTGACACTTTAATATTTCCTTTTTTTTTTGGAGACTATATTTATGCATTGAAAAAAAAAATGATGAAACAATTATTTTGAAAAATATATTTATGCCTACACGGAGGTTGGGAAGCAAATATTTTAATCAGAGAAATATTCCTTTTTTTTTTTTTTTAGTTGTACATTTTATAAGGGTTTGTACCCAGCACATGAAGTATAATGGTCAGATTCCTATTTTGTATTTATTTACCATTATAACCACTTTTTTAGGAAAAAAAAATAGTTGTTTTTGTATTTATATGTAACCAACAGAGAAAATATAGGGTTTGTAAATATGTTCCTGAATGCAGATTCAGCGTTTTTTTCTTTTTTTAACTTATGTATACGCAGCTGGTTATATGGCAAGTTTTATATTTTCTACAAAGCTCATTTTTAAGGTCGTTCGTTATGGAAGTGATCACGGATTGGTCCATTCGCCAGTCCTCCATATTGTGCAATTAACATGCATTTTGCAATGTAGGAAGTCCGGTGTGCATTTAGAATTGGAATAACTGCCTGATACAACTACTGCCATTTTCAGTTGTTTTTTTTGCGAATTCATTTTGGGCCAGTAGAATTTTTTTTTTTTTTTCCTTTTTTATTTTTTTTTTCTTTAAAATTAAAGAAAAAAAAATAAAGCTTGGCGGGGTGGGAAGAACATTGGAAAGTGGCATGATTTAAAATAAAAAGTTCTTAAATTTGACAAAAGAGTTCAACTATCACGCGCACAAGTGCTTCTGGGATTCTACACAGCAGTAGCTTGGACTTTCTTAAAAATATCTTAAAAATATTTAATTTATTTAAAGATTTGTGTTTTTTTTCCCCCTTCTGCTGTTTTTTTTCTGCCTTTTTTGTTTTCTACTGAACTTTTCTCTCATCTACTTTTTTGTGTTACAATTTCTTTTCTTTTTTTTTTTTTCACCACGGTCTTTGCAGTCACCACTCTTTTTATTGCCTCGTGAATTTTGTGTTAAAGGACAACCATTTAAAAAAAAAAAAAAAAAAA	Refseq >NM_001085884\|Xenopus laevis bone morphogenetic protein 2 (bmp2-a), mRNA CGAGAGAGCGAGGAACCAGCGCACCGGCCGTGGATCAGCTGCTGCCTGACCTGCCTCTTGCGCTCCGGATCCAGAGACAATTCTCCTGCGCTAATGTCCGCGCCTTCACGTCCGCACGGGACCTCGCACTGACATCCCAGGAGAGCGGCTCGTTGCTGACGGACACGGCGATCAGTCGCAGCGACTATGAGCAGAAAGCGAAGGACTGGGCTGCGAGCAGACGCACAGACTCGCCCTGGGAAGGAGACGCGTGGAGTAAAAAGACTCGAGTGATGTGGGAAAAACACACGGACAGCAGAAAACCATCATCGAGACACAAAGTCGGCGGCGCACAGGTTGACAATGGTCGCTGGGATCCACTCTCTGCTCCTGCTGCTGTTTTACCAGGTCTTGCTGAGTGGCTGCACCGGACTGATACCCGAGGAAGGCAAGCGCAAGTATACGGAATCGGGTCGCTCGTCTCCCCAGCAGTCCCAGAGGGTCCTCAACCAGTTCGAGCTCCGGCTGCTCAGTATGTTTGGCTTGAAGAGGCGTCCGACGCCTGGCAAAAATGTTGTGATCCCACCCTACATGCTGGACTTGTACCACCTGCACTTGGCTCAGTTGGCTGCTGATGAAGGCACTTCTGCCATGGACTTCCAGATGGAGCGGGCAGCCAGCCGAGCAAATACAGTGAGGAGTTTCCACCATGAAGAATCCATGGAAGAAATTCCTGAGTCTCGTGAGAAAACAATCCAACGATTCTTCTTCAACCTTTCTTCAATTCCAAATGAGGAGCTGGTCACTTCTGCCGAGCTGCGGATTTTTCGAGAGCAGGTCCAAGAGCCCTTTGAAAGTGACAGCAGCAAATTGCATCGGATTAATATTTACGACATTGTCAAGCCAGCGGCGGCTGCCTCCCGGGGCCCTGTTGTGAGACTATTGGACACCAGACTGGTACATCATAATGAAAGCAAATGGGAAAGTTTTGATGTAACGCCGGCAATTGCGCGGTGGATTGCACATAAACAGCCTAACCATGGGTTTGTTGTTGAAGTGACTCACTTGGACAATGACAAAAATGTGCCTAAGAAGCATGTGAGGATTAGTAGGTCTTTAACCCCGGATAAAGATAACTGGCCTCAGATACGGCCATTGTTGGTAACTTTTAGCCATGATGGTAAAGGACATGCTCTTCACAAAAGACAAAAGCGCCAAGCTAGGCACAAACAACGTAAACGCCTTAAATCGAGCTGCAGGAGGCATCCGTTGTACGTAGATTTCAGCGACGTTGGTTGGAATGACTGGATTGTTGCCCCACCTGGGTATCATGCCTTTTACTGCCACGGGGAATGTCCTTTTCCACTGGCAGACCATTTAAACTCTACAAACCATGCAATCGTACAAACTTTGGTGAACTCTGTCAACACAAACATCCCCAAAGCTTGCTGCGTCCCCACAGAACTCAGTGCCATATCCATGCTCTATCTTGATGAGAATGAAAAGTAGTATTAAAAAATTATCAAGACATGGTCGTGGAGGGGTGCGGATGCCGTTAGGCAGTTACGCGCAAGCCAGAGACAAGAAAGATGACACTTTAATATTTCCTTTTGGAGACTATATTTATGCTTTGAAAAATGATGAAACAATTATTTTGAAAATATATTTATGTCTACACGGAGGTTGGGAAGCAAATATTTTAATCAGAGAAATATTCCTTTTTTTAGTTGTACATTTTTATAAGGGTTTGTACCCAGCACATGAAGTATAATGGTCAGATTCCTATTTTGTATTTATTTACCATTATAACCACTTTTTTAGGGAAAAAATAGCTGTTTTGTATTTATATGTAATCAACAGAGAAAATATAGGGTTTGTAAAAATGTTACTGAAAGCAGATTCATTGGTTTTCTTTTTTTAAGTTATACACAGCTGGTTATATGGCAAGTGTTATATTTTCTACAAAGCTAATTTTAAGGTCAGTTGTTATAAAAATGATAATGTGTTGGTTCATTTTTATATCCTTCATATTGTGCCATTAACATGCATTTTTTAAAATGTAGGAAGTCCAGTGTGCATTGCTTTGTAAATTCAGAATTGGAATTCATACACGTAACTGTCGAATACAACTACTGCCATTTTCAAATAATTTTCTTCTTTTTTTGCGAATTGGTTTGGGCCAGTAGAATTTTTTTTTTCCTGAAGAATTTACAAAAAATAAAGCTTGGCTGGGTGGGAAGAACATTGCAAAGTGGCATGGTATAAAAATAAAATGTTCTTAAATTGGACAAATTCAAATATCACACACAACAATAGCTCGGATATCTCTTAAAAATATTTAATTTATTTAAAATATCTTAAGCCCTAAAAAAATTTGCGTTTGTTTTCTTCTGCTATTTTTTCTAATCTTTTTTTTTTTGTTTTGTTTTTCTACTGAACTTTCATCTACTAGCTACTTGTGTTATAATTTCTTCTTGAGTTTTCACCACAGTCACCACTTTTTTTTTTTCTTTTTTTTTTTTATTGCCTCATAAATTTTGTGTTAAAGGAACAGTTTAAAAAAAAAAAAAAAAGTTCAAAATGTCAAGATTTCACCAATAAATGAAGAAGTACAGACTTCCAGTACTGTTAATGTAAAAAAAAAAAAAAAA		Refseq >NM_001101666\|Xenopus laevis bone morphogenetic protein 2 (bmp2-b), mRNA GAATTCTCTTCCCTCTCACCGGCCTCTCGTCTCTACTCACCTCCCGGCGACCCCGGCTGGACTGAGACACTCGCTGCCACTATGTGCGACAACTCACCGACTGGGCTCGACTGGACGCGCGGACTTGTCTCCCTCCTCTGGGGACCAGCGACTTGAACTAAAGACTCGAGTGATTGTGGAAAAAACACGCGGGGAGCAGAAAACCCACATCGAGACACAAACTCGGCGACTAAATCGCTCAGGTTGACAATGGTCGCTGGGATCCACTCTCTGCTCCTGCTGCAGTTTTACCAGATCTTGCTGAGCGGCTGCACCGGGCTCGTCCCAGAGGAAGGCAAACGCAAGTATTCCGAATCCACTCGCTCGTCTCCGCAGCAGTCCCAACAAGTCCTCGACCAGTTTGAGCTTCGGCTGCTCAATATGTTCGGCTTGAAGAGGAGGCCGACGCCTGGCAAAAATGTTGTGATCCCCCCCTACATGTTGGACTTGTACCACCTGCACTCGGCTCAGTTGGCCGATGATCAAGGAAGTTCTGAGGTGGACTATCACATGGAGCGGGCGGCTAGCAGAGCCAACACAGTGAGGAGCTTTCACCATGAAGAATCCATGGAAGAAATTCCAGAGTCTGGTGAGAAAACAATCCAACGATTCTTCTTCAACCTTTCTTCAATTCCAGATGAGGAGCTGGTCACGTCTTCTGAGCTCCGGATTTTTCGAGAGCAGGTCCAAGAGCCATTTAAGACTGACGGCAGCAAACTTCATCGGATTAATATTTATGACATTGTCAAGCCAGCGGCGGCTGCCTCCCGGGGCCCTGTTGTAAGACTATTGGACACCAGACTGATCCATCATAATGAAAGCAAATGGGAAAGTTTTGATGTGACGCCGGCAATTACACGGTGGATTGCACATAAACAGCCTAACCATGGGTTTGTTGTTGAAGTGACTCACTTGGACAATGACACAAATGTGCCCAAGAGGCATGTGAGGATTAGTAGGTCTTTAACCCTGGATAAAGGTCACTGGCCTCGGATACGGCCATTATTGGTAACTTTTAGCCATGATGGCAAAGGACATGCTCTTCACAAAAGACAAAAACGGCAAGCTAGGCACAAACAACGTAAACGCCTTAAATCGAGCTGCAGGAGGCATCCGTTGTACGTAGATTTCAGTGACGTTGGTTGGAATGACTGGATTGTTGCCCCACCTGGGTATCATGCCTTTTACTGCCACGGGGAATGTCCTTTTCCACTGGCAGACCATTTAAACTCTACAAACCATGCAATCGTACAAACTTTGGTGAATTCCGTCAACACAAACATTCCCAAAGCTTGCTGCGTCCCCACAGAACTCAGTGCCATCTCCATGCTCTATCTTGATGAGAATGAAAAAGTAGTATTAAAGAATTATCAAGACATGGTCGTGGAGGGGTGCGGGTGCCGTTAGGCGGGGACACACAAGCCAGAGACAAGAAAGCTGACACTTTAATATTTCCTTTTGGAGACTATATTTATGCTTTGAAAAATGATGAAACAATTATTTTGAAAATATATTTATGTCTACACGGAGGCTGGGAAGCAAATATTTTAATCAGAGAAATATTCCTTTTTAGTTGTACATTTTTATAAGGGTTTGTACCCAGCACATGAAGTATAATGGTCAGATTCCTATTTTGTATTTATTTACCATTATAACCACTTTTTAAGGAAAAAAATAGCTGTTTTGTATTTATATGTAATCAACAGAGAAAATATAGGGTTTGTAAATATGTTACTGAAAGTGTTTTTTTCTTCTTTTTTTTAAATTATGTATACACAGCTGGTTATATGGCAAGTTTTTTATATTTTCTATAAAGCTAATTTCAAGGTCATTAGTTATAAACTTGATGATGTGTTGGTTCATTGGTAAATCCTCCATATTGTGCAATTAACATGCATTTTTATAATGTACGAAGTCCAGTCCATTGTGCATTGCTTTGCAAATTTAGAATTC
Protein		Refseq >NP_001015963\|bone morphogenetic protein 2 precursor [Xenopus (Silurana) tropicalis] MVAGIHSLLLLLFYQILLSGCTGLIPEEGKRKYTESGRSSPQHSQSVLNQFELRLLNMFGLKRRPTPGKNIVIPPYMLDLYHLHSGQLAADQDSSPMDYQIERAASRANTVRSFHHEESMEEIPESGEKTIQRFFFNLSSVPNEELVTSAELRIFREGVQEPFEGDSSKLHRINIYDIVKPAAAASRGPVVRLLDTRLIHHNESKWESFDVTPAITRWIAHKQPNHGFVVEVTHLDNDKNVPKKHVRISRSLVPDKDSWPRIRPLLVTFSHDGKGHALHKREKRQARHKQRKRLKSSCRRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNNVNPNIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR	Refseq >NP_001079353\|bone morphogenetic protein 2-A precursor [Xenopus laevis] MVAGIHSLLLLLFYQVLLSGCTGLIPEEGKRKYTESGRSSPQQSQRVLNQFELRLLSMFGLKRRPTPGKNVVIPPYMLDLYHLHLAQLAADEGTSAMDFQMERAASRANTVRSFHHEESMEEIPESREKTIQRFFFNLSSIPNEELVTSAELRIFREQVQEPFESDSSKLHRINIYDIVKPAAAASRGPVVRLLDTRLVHHNESKWESFDVTPAIARWIAHKQPNHGFVVEVTHLDNDKNVPKKHVRISRSLTPDKDNWPQIRPLLVTFSHDGKGHALHKRQKRQARHKQRKRLKSSCRRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNTNIPKACCVPTELSAISMLYLDENEK UniProtKB		Refseq >NP_001095136\|bone morphogenetic protein 2-B precursor [Xenopus laevis] MVAGIHSLLLLQFYQILLSGCTGLVPEEGKRKYSESTRSSPQQSQQVLDQFELRLLNMFGLKRRPTPGKNVVIPPYMLDLYHLHSAQLADDQGSSEVDYHMERAASRANTVRSFHHEESMEEIPESGEKTIQRFFFNLSSIPDEELVTSSELRIFREQVQEPFKTDGSKLHRINIYDIVKPAAAASRGPVVRLLDTRLIHHNESKWESFDVTPAITRWIAHKQPNHGFVVEVTHLDNDTNVPKRHVRISRSLTLDKGHWPRIRPLLVTFSHDGKGHALHKRQKRQARHKQRKRLKSSCRRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNTNIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.16734	Xl.1138		Xl.1140 [+] Xl.12641
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		15 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	BMP2	OMIM:235200
mouse		MGI	Bmp2	All(10) Targeted, knock Out(3) Targeted, other(5)
zebrafish		ZFIN ZFIN	bmp2b bmp2a	20 Lines(s)

Publications
First:		cDNA sequence of Xenopus laevis bone morphogenetic protein 2 (BMP-2). [Biochim Biophys Acta 1991]
Most recent:		Tcf21 regulates the specification and maturation of proepicardial cells. [Development 2013]
		View All Papers 7 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		growth factor activity
Biological:		growth
Cellular Component:		extracellular region
EC:
KOG:		[T] Transforming growth factor beta, bone morphogenetic protein and related proteins

Reagents		tropicalis	laevis a		laevis b
Clones		EXRC - 2 clone(s)	EXRC - 2 clone(s)
		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.16734.1.S1_at	Xl.1138.1.S1_at		Xl.1140.1.S1_s_at [+] Xl.1140.1.S1_at
Affymetrix 2.0			Xl2.1138.1.S1_at		Xl2.1140.2.S1_at [+] Xl2.1140.2.S1_x_at Xl2.12641.1.A1_at

Symbol legend[+]