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Summary Expression Gene Literature (853) GO Terms (30) Nucleotides (231) Proteins (33) Interactants (1417) Wiki
XB-GENEPAGE-481981
Gene Symbol:
zic1

Gene Name:
Zic family member 1

Synonyms:
Zic-r1 , opl , odd-paired-like , Zic-related-1 ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type

Protein Function :
Transcriptional activator that induces expression of multiple genes including pax3, en2, snai2/slug, feb and a subset of wnt genes. Has multiple key roles in the regulation of neural induction and neur...[+]


InterPro :
EXOC6/Sec15 C dom1 , EXOC6/Sec15

Interactants:
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Diseases: 


OMIM:
CRANIOSYNOSTOSIS 6; CRS6

External Links:
1/5
 
Xenbase Gene ID XB-GENE-481982 XB-GENE-17336404 XB-GENE-864815
Gene Symbol zic1 zic1.L zic1.S
Chromosome Chr05 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 8.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100038076
108717075
399124
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine zic1 zic1.L zic1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ZIC1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Zic1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Zic1 Ensembl
zebrafish
ZFIN, AGR zic1 ZFIN Ensembl
chicken
GEISHA ZIC1 Ensembl
fruit fly
worm
Publications
First Uptake of 3H-glycine in the outer plexiform layer of the retina of the toad, Bufo marinus., J Comp Neurol 1984  
Most Recent PR domaincontaining protein 12 (prdm12) is a downstream target of the transcription factor zic1 during cellular differentiation in the central nervous system: PR domain containing protein is the right form., Int J Dev Neurosci 2020  
All View All Papers 31 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 11 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 4 terms 16 terms
PANTHER zic1
KEGG Pathways K09224 K09224
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks
Morpholinos zic1 MO1 zic1 MO1 zic1 MO1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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