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Summary Expression Gene Literature (39) GO Terms (9) Nucleotides (197) Proteins (58) Interactants (103) Wiki
XB-GENEPAGE-482045
Gene Symbol:
tbl1xr1

Gene Name:
transducin (beta)-like 1 X-linked receptor 1

Synonyms:
TBLR1 , tbl1xr1-a , tbl1xr1-b ( Add synonyms , Nomenclature history )

Gene Function:
Beta-transducin family (WD-40 repeat) protein

Protein Function :
F-box-like protein which acts as an integral component of the N-CoR transcriptional corepressor complex. Probably regulates transcription activation mediated by nuclear receptors. May mediate the recru...[+]



Interactants:
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Diseases: 


Disease Ontology:
autosomal dominant non-syndromic intellectual disability 41

OMIM:
PIERPONT SYNDROME; PRPTS [+]

External Links:
 
Xenbase Gene ID XB-GENE-482046 XB-GENE-6255786 XB-GENE-864821
Gene Symbol tbl1xr1 tbl1xr1.L tbl1xr1.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 550028
398608
779369
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tbl1xr1 tbl1xr1.L tbl1xr1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TBL1XR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tbl1xr1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tbl1xr1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tbl1xr1b tbl1xr1a ZFIN Ensembl
chicken
GEISHA TBL1XR1 Ensembl
fruit fly
worm
Publications
First Fusion protein of retinoic acid receptor alpha with promyelocytic leukemia protein or promyelocytic leukemia zinc finger protein recruits N-CoR-TBLR1 corepressor complex to repress transcription in vivo., J Biol Chem 2003  
Most Recent A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes., Nucleic Acids Res 2016                                
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 2 terms 2 terms
PANTHER tbl1xr1
KEGG Pathways K04508 K04508 K04508
KOG [B] Beta-transducin family (WD-40 repeat) protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tbl1xr1
ORFs tbl1xr1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list