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Summary Expression Gene Literature (246) GO Terms (21) Nucleotides (99) Proteins (50) Interactants (2167) Wiki
XB-GENEPAGE-482192
Gene Symbol:
esr1

Gene Name:
estrogen receptor 1

Synonyms:
ERalpha , ERbeta , xlERalpha1 , xlERalpha2 , XER , nr3a1 , xesr-1 , xesr1 , esr1-a , esr1-b ( Add synonyms , Nomenclature history )

Gene Function:
steroid hormone receptor

Protein Function :
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
breast cancer [+]

OMIM:
MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-482193 XB-GENE-864840 XB-GENE-6255445
Gene Symbol esr1 esr1.L esr1.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394461
398734
398733
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine esr1 esr1.L esr1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ESR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Esr1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Esr1 Ensembl
zebrafish
ZFIN, AGR esr1 ZFIN Ensembl
chicken
GEISHA ESR1 Ensembl
fruit fly
worm
Publications
First The Xenopus laevis estrogen receptor: sequence homology with human and avian receptors and identification of multiple estrogen receptor messenger ribonucleic acids., Mol Endocrinol 1987  
Most Recent Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment., Toxicol In Vitro 2020  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 8 terms 8 terms
PANTHER esr1
KEGG Pathways K08122 [+] K08550 K08550
KOG [T] FOG: Hormone receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks esr1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list