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XB-GENEPAGE-482218
Gene Symbol:
nkx2-2
Gene Name: NK2 homeobox 2
Synonyms:
XeNK-2
,
nkx2.2
,
Xnkx2.2
( Gene Function: homeodomain transcription factor Protein Function
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Defines dorsal-ventral domains in developing brain. May play a role in defining positional information along the anterior-posterior (a/p) axis and the dorsal-ventral (d/v) axis of the developing nervou...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-482219 | XB-GENE-17336182 | XB-GENE-864842 | |||||
Gene Symbol | nkx2-2 | nkx2-2.L | nkx2-2.S | Chromosome | Chr5 | chr5L | chr5S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100038077
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108716603
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373624
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | nkx2-2 | nkx2-2.L | nkx2-2.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
A Xenopus homebox gene defines dorsal-ventral domains in the developing brain., Development 1993 ![]() |
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Most Recent |
Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Front Physiol 2019 ![]() |
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All | View All Papers 7 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 21 terms | 5 terms | 6 terms | |||||
PANTHER | nkx2-2 | |||||||
KEGG Pathways | K08029 | K08029 | K08029 | |||||
KOG |
[K] Transcription factor tinman/NKX2-3, contains HOX domain
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | nkx2-2 | |||||||
Antibodies | Nkx2-2 Ab1 | |||||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



