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Summary Expression Gene Literature (21) GO Terms (18) Nucleotides (44) Proteins (19) Interactants (298) Wiki
XB-GENEPAGE-482418

Gene Symbol: hnf4a

Gene Name: hepatocyte nuclear factor 4 alpha

Synonyms: HNF-4-alpha , hnf4 , nr2a1 ( Add synonyms , Nomenclature history )

Gene Function: steroid hormone receptor, transcription factor

Protein Function :
Transcriptional regulator; binds and activates the promoter for the HNF1-alpha gene (PubMed:8808405). Potential initiator of a transcriptional cascade within a subset of cells committed to a specific d...[+]

Interactants: Loading ...
Disease Ontology: maturity-onset diabetes of the young [+]

OMIM Diseases: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]

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Xenbase Gene ID XB-GENE-482419 XB-GENE-17337466 XB-GENE-864872
Gene Symbol hnf4a hnf4a.L hnf4a.S
Chromosome Chr10 Scaffold14557
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine hnf4a hnf4a.L hnf4a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HNF4A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Hnf4a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR hnf4a ZFIN Ensembl
chicken
GEISHA HNF4A Ensembl
fruit fly
worm
WORMBASE
Publications
First Elements and factors involved in tissue-specific and embryonic expression of the liver transcription factor LFB1 in Xenopus laevis., Mol Cell Biol 1993  
Most Recent Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers., Elife 2019                                        
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 0 term 0 term
PANTHER hnf4a
KEGG Pathways K07292
KOG [K] Hepatocyte nuclear factor 4 and similar steroid hormone receptors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
ORF hnf4a.S ORF1
Affymetrix 1.0 Str.36814.2.S1_at [+] Xl.1217.1.S1_at [+]
Affymetrix 2.0 Xl2.1217.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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