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Summary Expression Gene Literature (21) GO Terms (33) Nucleotides (53) Proteins (27) Interactants (300) Wiki
XB-GENEPAGE-482418
Gene Symbol:
hnf4a

Gene Name:
hepatocyte nuclear factor 4 alpha

Synonyms:
HNF-4-alpha , hnf4 , nr2a1 ( Add synonyms , Nomenclature history )

Gene Function:
steroid hormone receptor, transcription factor

Protein Function :
Transcriptional regulator; binds and activates the promoter for the HNF1-alpha gene (PubMed:8808405). Potential initiator of a transcriptional cascade within a subset of cells committed to a specific d...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
maturity-onset diabetes of the young [+]

OMIM:
DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]

External Links:
1/7
 
Xenbase Gene ID XB-GENE-482419 XB-GENE-17337466 XB-GENE-864872
Gene Symbol hnf4a hnf4a.L hnf4a.S
Chromosome Chr10 chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100492541
379762
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hnf4a hnf4a.L hnf4a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HNF4A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hnf4a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hnf4a Ensembl
zebrafish
ZFIN, AGR hnf4a ZFIN Ensembl
chicken
GEISHA HNF4A Ensembl
fruit fly
worm
Publications
First Elements and factors involved in tissue-specific and embryonic expression of the liver transcription factor LFB1 in Xenopus laevis., Mol Cell Biol 1993  
Most Recent Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers., Elife 2019                                        
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 30 terms 0 term 13 terms
PANTHER hnf4a
KEGG Pathways K07292 K07292
KOG [K] Hepatocyte nuclear factor 4 and similar steroid hormone receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hnf4a
ORFs hnf4a.S ORF1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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