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Summary Expression Gene Literature (15) GO Terms (16) Nucleotides (151) Proteins (46) Interactants (324) Wiki
XB-GENEPAGE-482613
Gene Symbol:
tnnt2

Gene Name:
troponin T2, cardiac type

Synonyms:
CT3 ( Add synonyms , Nomenclature history )

Gene Function:
Troponin

Protein Function :
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.


InterPro :
TSP1 rpt sf , LDL receptor-like sf , LDLR class-A CS , MACPF [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypertrophic cardiomyopathy 2 [+]

OMIM:
CARDIOMYOPATHY, DILATED, 1D; CMD1D [+]

External Links:
 
Xenbase Gene ID XB-GENE-482614 XB-GENE-1188074 XB-GENE-17346591
Gene Symbol tnnt2 tnnt2.L tnnt2.S
Chromosome Chr02 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100493699
446916
398518
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tnnt2 tnnt2.L tnnt2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TNNT2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tnnt2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tnnt2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tnnt2a tnnt2b ZFIN Ensembl
chicken
GEISHA TNNT2 Ensembl
fruit fly
worm
Publications
First Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway., Development 1999          
Most Recent The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Dev Biol 2019                                    
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 2 terms 0 term
PANTHER tnnt2
KEGG Pathways K12045
KOG [Z] Troponin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tnnt2
Antibodies Tnnt2 Ab1
ORFs MGC132191 ORF1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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