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Summary Expression Gene Literature (390) GO Terms (39) Nucleotides (90) Proteins (39) Interactants (605) Wiki
XB-GENEPAGE-482643
Gene Symbol:
gli1

Gene Name:
GLI family zinc finger 1

Synonyms:
Gli-1 , X-gli1 ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type

Protein Function :
Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. May regulate the transcription of specific genes during normal development (PubMed:9216996). Mediates SHH signa...[+]


Antibodies: :
Gli1 Ab2


Interactants:
Loading ...

Diseases: 


Disease Ontology:
Ellis-Van Creveld syndrome

OMIM:
POLYDACTYLY, POSTAXIAL, TYPE A8; PAPA8

External Links:
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Xenbase Gene ID XB-GENE-482644 XB-GENE-17336681 XB-GENE-864895
Gene Symbol gli1 gli1.L gli1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100494064
108708587
398350
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gli1 gli1.L gli1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GLI1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gli1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gli1 Ensembl
zebrafish
ZFIN, AGR gli1 ZFIN Ensembl
chicken
GEISHA GLI1 Ensembl
fruit fly
worm
Publications
First Gli1 is a target of Sonic hedgehog that induces ventral neural tube development., Development 1997                    
Most Recent Thyroid hormone-induced expression of Foxl1 in subepithelial fibroblasts correlates with adult stem cell development during Xenopus intestinal remodeling., Sci Rep 2020                
All View All Papers 7 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 34 terms 10 terms 13 terms
PANTHER gli1
KEGG Pathways K16797 K16797 K16797
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gli1
Antibodies Gli1 Ab2 Gli1 Ab2 Gli1 Ab2
Morpholinos gli1 MO1 gli1 MO1 gli1 MO1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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