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Summary Expression Gene Literature (71) Nucleotides (136) Proteins (35) Interactants (312) Wiki
XB-GENEPAGE-482739

Gene Symbol: pax3

Gene Name: paired box 3

Synonyms: pax-3, Waardenburg syndrome 1, xpax3 Add Xenopus synonyms

Gene Function: paired box transcription factor with homeodomain

Interactants: snai2(34) , sox2(24) , myod1(21) , foxd3(19) , msx1(19) , sox3(15) , zic1(15) View All
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  XB-GENE-482740 XB-GENE-482744   XB-GENE-6252072
Molecules tropicalis laevis a laevis b
Gene JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1 JGI XL Genome 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq UniProtKB Refseq UniProtKB Refseq UniProtKB
Genomic tropicalis
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Synteny Metazome
Expression tropicalis laevis a laevis b
UniGene Str.44149 Xl.49495 Xl.54870
Unigene EST Profile EST Profile EST Profile EST Profile
GEO data GEO GEO
Images 160 expression image(s) for tropicalis and laevis
Orthology MOD Entrez Gene Genetic Phenotypes Morphants
human OMIM:Gene, HGNC PAX3 OMIM:122880 OMIM:268220 OMIM:193500 OMIM:148820
mouse MGI Pax3 All(32) Targeted, knock Out(2) Targeted, other(15) Radiation Induced(5) Chemically Induced(2) Spontaneous(5)
zebrafish ZFIN ZFIN pax3a pax3b 3 Lines(s)
Publications
First: Primitive streak mesoderm-like cell lines expressing Pax-3 and Hox gene autoinducing activities. [Development 1994]
Most recent: Pax3 and Zic1 drive induction and differentiation of multipotent, migratory, and functional neural crest in Xenopus embryos. [Proc Natl Acad Sci U S A 2013]
View All Papers 31 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding
transcription factor activity
      Biological: multicellular organismal development
regulation of transcription, DNA-dependent
      Cellular Component: nucleus
EC:
KOG: [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis a laevis b
Clones EXRC - 2 clone(s) EXRC - 1 clone(s) EXRC - 1 clone(s)
open biosystems open biosystems open biosystems
geneservice/RZPD imagenes geneservice/RZPD imagenes geneservice/RZPD imagenes
Affymetrix 1.0 Str.11142.1.S1_a_at [+] Xl.25932.2.A1_s_at
Affymetrix 2.0 Xl2.49495.3.S1_x_at [+] Xl2Affx.25.1.S1_at [+]

Symbol legend[+]