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Summary Expression Gene Literature (43) GO Terms (9) Nucleotides (70) Proteins (29) Interactants (668) Wiki
XB-GENEPAGE-483145
Gene Symbol: six6

Gene Name: SIX homeobox 6

Synonyms: XOptx2 , Six6.1 , xSix6 , optx2 , optic six gene 2 , XSix6.1 , xsix6.2 , six6.2 , XSix3 , hpe2 ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :

Interactants: Loading ...
Diseases:  Disease Ontology: microphthalmia

OMIM: OPTIC DISC ANOMALIES WITH RETINAL AND/OR MACULAR DYSTROPHY; ODRMD [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/6
 
Xenbase Gene ID XB-GENE-483146 XB-GENE-864947 XB-GENE-1021810
Gene Symbol six6 six6.L six6.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100101705
398128
373784
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine six6 six6.L six6.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SIX6 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Six6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR six6a six6b ZFIN Ensembl
chicken
GEISHA SIX6 Ensembl
fruit fly
worm
WORMBASE
Publications
First The genetic sequence of retinal development in the ciliary margin of the Xenopus eye., Dev Biol 1998                      
Most Recent miR-199 plays both positive and negative regulatory roles in Xenopus eye development., Genesis 2020                          
All View All Papers 9 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 4 terms 4 terms
PANTHER six6
KEGG Pathways K19473 K19473 K19473
KOG [K] Transcription factor SIX and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks six6
ORFs six6 ORF1 six6.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.13.0


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