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Summary Expression Gene Literature (43) GO Terms (9) Nucleotides (89) Proteins (41) Interactants (679) Wiki
XB-GENEPAGE-483145
Gene Symbol:
six6

Gene Name:
SIX homeobox 6

Synonyms:
XOptx2 , Six6.1 , xSix6 , optx2 , optic six gene 2 , XSix6.1 , xsix6.2 , six6.2 , XSix3 , hpe2 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :


InterPro :
Diacylglycerol kinase cat dom , Diacylglycerol kin accessory , PE/DAG-bd , ATP-NAD kinase N [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
microphthalmia [+]

OMIM:
OPTIC DISC ANOMALIES WITH RETINAL AND/OR MACULAR DYSTROPHY; ODRMD [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-483146 XB-GENE-864947 XB-GENE-1021810
Gene Symbol six6 six6.L six6.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101705
398128
373784
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine six6 six6.L six6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SIX6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Six6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Six6 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR six6a six6b ZFIN Ensembl
chicken
GEISHA SIX6 Ensembl
fruit fly
worm
Publications
First The genetic sequence of retinal development in the ciliary margin of the Xenopus eye., Dev Biol 1998                      
Most Recent miR-199 plays both positive and negative regulatory roles in Xenopus eye development., Genesis 2020                          
All View All Papers 9 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 4 terms 4 terms
PANTHER six6
KEGG Pathways K19473 K19473 K19473
KOG [K] Transcription factor SIX and related HOX domain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks six6
ORFs six6 ORF1 six6.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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