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Summary Expression Gene Literature (63) GO Terms (33) Nucleotides (76) Proteins (34) Interactants (454) Wiki
XB-GENEPAGE-483163
Gene Symbol:
runx1

Gene Name:
RUNX family transcription factor 1

Synonyms:
Xaml , aml1 oncogene , aml-1 , Runx-1 , aml1 , aml , cbfa2 , evi-1 , amlcr1 , pebp2ab , aml1-evi-1 , Xaml1 ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional regulator

Protein Function :
Involved in primitive hematopoiesis in the embryo.


InterPro :
Znf MYND , TAFH/NHR1 dom sf , NHR2 , CBFA2T1 [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
rheumatoid arthritis [+]

OMIM:
RHEUMATOID ARTHRITIS; RA [+]

External Links:
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Xenbase Gene ID XB-GENE-483164 XB-GENE-864949 XB-GENE-17344131
Gene Symbol runx1 runx1.L runx1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100485449
379657
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine runx1 runx1.L runx1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards RUNX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Runx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Runx1 Ensembl
zebrafish
ZFIN, AGR runx1 ZFIN Ensembl
chicken
GEISHA RUNX1 Ensembl
fruit fly
worm
Publications
First Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines., Cell 1988  
Most Recent In vitro inhibition of human nucleoside transporters and uptake of azacitidine by an isocitrate dehydrogenase-2 inhibitor enasidenib and its metabolite AGI-16903., Xenobiotica 2019  
All View All Papers 14 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 29 terms 8 terms 0 term
PANTHER runx1
KEGG Pathways K08367
KOG [K] Runt and related transcription factors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks runx1
Mutants Xtr.runx1emHorb
Morpholinos (on-target & off-target) runx1 MO1 , runx1 MO2 , runx1 MO3 runx1 MO1 , runx1 MO2 , runx1 MO3
ORFs runx1.L ORF1
Clones Horizon EXRC Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info