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Summary Expression Gene Literature (76) GO Terms (13) Nucleotides (142) Proteins (45) Interactants (1545) Wiki
XB-GENEPAGE-483192
Gene Symbol:
hesx1

Gene Name:
HESX homeobox 1

Synonyms:
rpx , Xanf1 , Xanf-1 , Xanf , XANF-2 , Xanf2 , anf2 , hesx1-b , hesx1-a ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Regulates the earliest stages of development of the anterior neural plate. Plays a role in forebrain development by inhibiting the expression of otx2 and pax6 in the rostral region of the anterior neur...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
septooptic dysplasia

OMIM:
SEPTOOPTIC DYSPLASIA

External Links:
1/3
 
Xenbase Gene ID XB-GENE-483193 XB-GENE-864952 XB-GENE-6252654
Gene Symbol hesx1 hesx1.L hesx1.S
Chromosome scaffold_87 Scaffold24 Scaffold40
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549466
397950
378542
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hesx1 hesx1.L hesx1.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tneu069m07      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HESX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hesx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hesx1 Ensembl
zebrafish
ZFIN, AGR hesx1 ZFIN Ensembl
chicken
GEISHA HESX1 Ensembl
fruit fly
worm
Publications
First A novel homeobox gene expressed in the anterior neural plate of the Xenopus embryo., Dev Biol 1992            
Most Recent Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos., Front Physiol 2020            
All View All Papers 19 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 7 terms 5 terms
PANTHER hesx1
KEGG Pathways K09354 K09354 K09354
KOG [R] Transcription factor, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hesx1
Morpholinos hesx1 MO1 , hesx1 MO2 , hesx1 MO3 , hesx1 MO4 hesx1 MO1 , hesx1 MO2 , hesx1 MO3 , hesx1 MO4 hesx1 MO1 , hesx1 MO2 , hesx1 MO3 , hesx1 MO4
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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