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XB-GENEPAGE-483208
Gene Symbol:
nodal
Gene Name: nodal growth differentiation factor
Synonyms:
Xnr-4
,
Xnr4
,
nr4
,
nodal4
,
Nodal homolog 4
( Gene Function: transforming growth factor beta and bone morphogenetic protein related protein Protein Function
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Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Plays a role in mesoderm formation and may be required for neural development.
Interactants:
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Diseases: Disease Ontology:
situs inversus
OMIM:
HETEROTAXY, VISCERAL, 5, AUTOSOMAL; HTX5
External Links:
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Xenbase Gene ID | XB-GENE-483209 | XB-GENE-864954 | XB-GENE-17339551 | |||||
Gene Symbol | nodal | nodal.L | nodal.S | Chromosome | Chr7 | chr7L | chr7S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100497218
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398068
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108697489
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | nodal | nodal.L | nodal.S | |||||
Phenotype | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Smith Morpholino Screen | tgas097d22 | |||||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments., Acta Physiol Scand 1973 |
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Most Recent |
Bruton''s Tyrosine Kinase Inhibition Promotes Myelin Repair., Brain Plast 2020 ![]() |
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All | View All Papers 91 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 18 terms | 3 terms | 3 terms | |||||
PANTHER | nodal | |||||||
KEGG Pathways | K04666 | K04666 | K04666 | |||||
KOG |
[T] Transforming growth factor beta, bone morphogenetic protein and related proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | nodal | |||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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