Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (81) GO Terms (11) Nucleotides (34) Proteins (17) Interactants (485) Wiki
XB-GENEPAGE-483330

Gene Symbol: pdx1

Gene Name: pancreatic and duodenal homeobox 1

Synonyms: ipf1 , XlHbox8 , pdx-1 , XlHbox-8 , STF-1 ( Add synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Acts together with ptf1a to induce the pancreatic lineage within the endoderm.

Interactants: Loading ...
Disease Ontology: pancreatic agenesis [+]

OMIM Diseases: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]

 
Xenbase Gene ID XB-GENE-483331 XB-GENE-17343771 XB-GENE-6464311
Gene Symbol pdx1 pdx1.L pdx1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine pdx1 pdx1.L pdx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PDX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pdx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR pdx1 ZFIN Ensembl
chicken
GEISHA PDX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm., Development 1989            
Most Recent Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation., Front Physiol 2019                
All View All Papers 14 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 3 terms 0 term
PANTHER pdx1
KEGG Pathways K07594 K07594
KOG [R] Transcription factor zerknullt and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Pdx1 Ab1 , Pdx1 Ab2 Pdx1 Ab1 , Pdx1 Ab2
Morpholino pdx1 MO1 pdx1 MO1 pdx1 MO1
Affymetrix 1.0 Str.51687.1.S1_at
Affymetrix 2.0

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.4


Major funding for Xenbase is provided by grant P41 HD064556