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Summary Expression Gene Literature (82) GO Terms (23) Nucleotides (50) Proteins (29) Interactants (499) Wiki
XB-GENEPAGE-483330
Gene Symbol:
pdx1

Gene Name:
pancreatic and duodenal homeobox 1

Synonyms:
ipf1 , XlHbox8 , pdx-1 , XlHbox-8 , STF-1 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Acts together with ptf1a to induce the pancreatic lineage within the endoderm.


InterPro :
dDENN dom , DENND1A/B/C , Tripartite DENN , cDENN dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
pancreatic agenesis [+]

OMIM:
DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]

External Links:
 
Xenbase Gene ID XB-GENE-483331 XB-GENE-17343771 XB-GENE-6464311
Gene Symbol pdx1 pdx1.L pdx1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100490648
108708702
100337610
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine pdx1 pdx1.L pdx1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PDX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pdx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pdx1 Ensembl
zebrafish
ZFIN, AGR pdx1 ZFIN Ensembl
chicken
GEISHA PDX1 Ensembl
fruit fly
worm
Publications
First XlHbox 8: a novel Xenopus homeo protein restricted to a narrow band of endoderm., Development 1989            
Most Recent Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2., Nat Commun 2019                        
All View All Papers 14 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 3 terms 4 terms
PANTHER pdx1
KEGG Pathways K07594 K07594 K07594
KOG [R] Transcription factor zerknullt and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pdx1
Antibodies Pdx1 Ab1 , Pdx1 Ab2 Pdx1 Ab1 , Pdx1 Ab2
Morpholinos pdx1 MO1 pdx1 MO1 pdx1 MO1
Clones Horizon Horizon Horizon Source BioScience

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