Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (66) Nucleotides (54) Proteins (22) Interactants (437) Wiki
XB-GENEPAGE-483692

Gene Symbol: pax8

Gene Name: paired box 8

Synonyms: XPax8, XPax-8, pax-8 Add Xenopus synonyms

Gene Function: paired box transcription factor

Interactants: pax2(34) , lhx1(28) , wt1(16) , myod1(14) , wnt4(11) , otx2(10) , slc12a1(10) View All

Disease Associations: HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 2; CHNG2
1/6
 
Xenbase Gene ID XB-GENE-483693 XB-GENE-865008
Current JGI Annotation pax8 pax8.L
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq UniProtKB Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.51436 Xl.2754
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 149 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC PAX8 OMIM:218700
mouse
MGI Pax8 All available mutants
zebrafish
ZFIN pax8 All
chicken
Publications
First: Molecular regulation of pronephric development. [Curr Top Dev Biol 1999]
Most recent: Transcriptional regulator PRDM12 is essential for human pain perception. [Nat Genet 2015]
View All Papers 31 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular:
      Biological: multicellular organismal development
      Cellular Component: nucleus
EC:
KOG: [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Pax8 Ab1 Pax8 Ab1
Morpholino pax8 MO1, pax8 MO2 pax8 MO1, pax8 MO2
Affymetrix 1.0 Str.51436.2.S1_s_at [+] Xl.2754.1.S1_at
Affymetrix 2.0 Xl2.2754.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [3.5.2]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556