|
XB-GENEPAGE-483692
Gene Symbol:
pax8
Gene Name: paired box 8
Synonyms:
XPax8
,
XPax-8
,
pax-8
( Gene Function: paired box transcription factor Protein Function
![]()
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae.
Interactants:
Loading ...
Diseases: Disease Ontology:
congenital nongoitrous hypothryoidism 2
OMIM:
HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 2; CHNG2
External Links:
|
|
Xenbase Gene ID | XB-GENE-483693 | XB-GENE-865008 | XB-GENE-17334490 | |||||
Gene Symbol | pax8 | pax8.L | pax8.S | Chromosome | Chr3 | chr3L | chr3S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.2
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
Gene model
![]() |
|||||
Entrez Gene |
780226
|
398132
|
108712742
|
|||||
mRNA |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
|||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
|||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
|
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | pax8 | pax8.L | pax8.S | |||||
Orthology |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
worm |
|
|||||||
Publications | ||||||||
First |
Molecular regulation of pronephric development., Curr Top Dev Biol 1999 ![]() |
|||||||
Most Recent |
Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism., Horm Res Paediatr 2020 |
|||||||
All | View All Papers 31 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 35 terms | 20 terms | 4 terms | |||||
PANTHER | pax8 | |||||||
KEGG Pathways | K09293 | K09293 | K09293 | |||||
KOG |
[K] Transcription factor PAX2/5/8, contains PAX domain
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | pax8 | |||||||
Antibodies | Pax8 Ab1 | Pax8 Ab1 | ||||||
Morpholinos (on-target & off-target) | pax8 MO2 , pax8 MO3 | pax8 MO1 , pax8 MO2 , pax8 MO3 | ||||||
ORFs | pax8 ORF1 | |||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



