Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (88) GO Terms (22) Nucleotides (87) Proteins (50) Interactants (1084) Wiki
XB-GENEPAGE-483692
Gene Symbol: pax8

Gene Name: paired box 8

Synonyms: XPax8 , XPax-8 , pax-8 ( Add synonyms , Nomenclature history )

Gene Function: paired box transcription factor

Protein Function :
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae.


Interactants: Loading ...
Disease Ontology: congenital nongoitrous hypothryoidism 2

OMIM Diseases: HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 2; CHNG2

1/11
 
Xenbase Gene ID XB-GENE-483693 XB-GENE-865008 XB-GENE-17334490
Gene Symbol pax8 pax8.L pax8.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 780226
Entrez Gene: 398132
Entrez Gene: 108712742
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot TrEMBL RefSeq TrEMBL Swiss-Prot NCBI Protein TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine pax8 pax8.L pax8.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PAX8 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pax8 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR pax8 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First Molecular regulation of pronephric development., Curr Top Dev Biol 1999      
Most Recent A Critical E-box in Barhl1 3'' Enhancer Is Essential for Auditory Hair Cell Differentiation., Cells 2019                
All View All Papers 31 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 19 terms 4 terms
PANTHER pax8
KEGG Pathways K09293 K09293 K09293
KOG [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)    
Horizon Horizon Horizon
Antibody Pax8 Ab1 Pax8 Ab1
Morpholino pax8 MO1 , pax8 MO2 , pax8 MO3 pax8 MO1 , pax8 MO2 , pax8 MO3 pax8 MO1 , pax8 MO2 , pax8 MO3
ORF pax8 ORF1
Affymetrix 1.0 Str.51436.2.S1_s_at [+] Xl.2754.1.S1_at
Affymetrix 2.0 Xl2.2754.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.3


Major funding for Xenbase is provided by grant P41 HD064556