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Summary Expression Gene Literature (88) GO Terms (29) Nucleotides (113) Proteins (56) Interactants (1086) Wiki
XB-GENEPAGE-483692
Gene Symbol:
pax8

Gene Name:
paired box 8

Synonyms:
XPax8 , XPax-8 , pax-8 ( Add synonyms , Nomenclature history )

Gene Function:
paired box transcription factor

Protein Function :
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae.


InterPro :
Pax2 C , Paired dom , WH-like DNA-bd sf , Homeobox-like sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
congenital nongoitrous hypothryoidism 2

OMIM:
HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 2; CHNG2

External Links:
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Xenbase Gene ID XB-GENE-483693 XB-GENE-865008 XB-GENE-17334490
Gene Symbol pax8 pax8.L pax8.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 780226
398132
108712742
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq RefSeq Swiss-Prot NCBI Protein
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine pax8 pax8.L pax8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PAX8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pax8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pax8 Ensembl
zebrafish
ZFIN, AGR pax8 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Molecular regulation of pronephric development., Curr Top Dev Biol 1999      
Most Recent A Critical E-box in Barhl1 3'' Enhancer Is Essential for Auditory Hair Cell Differentiation., Cells 2019                
All View All Papers 31 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 27 terms 19 terms 4 terms
PANTHER pax8
KEGG Pathways K09293 K09293 K09293
KOG [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pax8
Antibodies Pax8 Ab1 Pax8 Ab1
Morpholinos pax8 MO1 , pax8 MO2 , pax8 MO3 pax8 MO1 , pax8 MO2 , pax8 MO3 pax8 MO1 , pax8 MO2 , pax8 MO3
ORFs pax8 ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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