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Summary Expression Gene Literature (264) GO Terms (29) Nucleotides (111) Proteins (56) Interactants (301) Wiki
XB-GENEPAGE-483702
Gene Symbol:
pomc

Gene Name:
proopiomelanocortin

Synonyms:
proopiomelanocortin , alpha-MSH , alpha-melanophore stimulating hormone , aMSH , ACTH , adrenocorticotropic hormone , pomc-a , pomc-b , corticotropin ( Add synonyms , Nomenclature history )

Gene Function:
polypeptide hormone precursor

Protein Function :
Endogenous opiate.[+]


InterPro :
Mcrtin ACTH cent , PMOC , Melanocortin N , Opioid neuropept [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
obesity

OMIM:
OBESITY [+]

External Links:
 
Xenbase Gene ID XB-GENE-483703 XB-GENE-483707 XB-GENE-6252423
Gene Symbol pomc pomc.L pomc.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496777
380532
373802
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pomc pomc.L pomc.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards POMC OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pomc MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pomc Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pomca pomcb ZFIN Ensembl
chicken
GEISHA POMC Ensembl
fruit fly
worm
Publications
First The effect of ACTH and corticosteroids on carbohydrate metabolism during the metamorphosis of Xenopus laevis., Gen Comp Endocrinol 1971  
Most Recent Pharmacological evaluation of MRAP proteins on Xenopus neural melanocortin signaling., J Cell Physiol 2021  
All View All Papers 1 paper(s) referencing OMIMs
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 29 terms 3 terms 3 terms
PANTHER pomc
KEGG Pathways K05228 K05228 K05228
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pomc
Antibodies Pomc Ab1 , Pomc Ab2 , Pomc Ab3 Pomc Ab3 Pomc Ab3
ORFs pomc ORF1 pomc.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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