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Summary Expression Gene Literature (5) GO Terms (8) Nucleotides (65) Proteins (30) Interactants (38) Wiki
XB-GENEPAGE- 483775

Gene Symbol: hmx3

Gene Name: H6 family homeobox 3

Synonyms: nkx5.1 , nkx5-1 , nkx-5.1
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. May act as a stage-speci...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-483776 XB-GENE-865014 XB-GENE-17332109
Gene Symbol hmx3 hmx3.L hmx3.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq NCBI Nucleotide
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.40296 Xl.19182
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 3 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine hmx3 hmx3.L hmx3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
HMX3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hmx3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN hmx3a hmx3b ZFIN Ensembl
chicken
GEISHA HMX3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox. [Development 1996]
Most recent: PAPC and the Wnt5a/Ror2 pathway control the invagination of the otic placode in Xenopus. [BMC Dev Biol 2011]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 6 terms 3 terms
EC
PANTHER hmx3
KEGG Pathways K09349 K09349 K09349
KOG [K] Transcription factor NKX-5.1/HMX1, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino hmx3 MO1 hmx3 MO1 hmx3 MO1
Affymetrix 1.0 Str.40296.1.S1_at Xl.19182.1.S1_at
Affymetrix 2.0 Xl2.19182.1.S1_at

Symbol legend[+]

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