Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (18) GO Terms (23) Nucleotides (101) Proteins (41) Interactants (148) Wiki
XB-GENEPAGE-484011
Gene Symbol:
acvr2a

Gene Name:
activin A receptor type 2A

Synonyms:
acvr2 , actrii , XSTK9 , XAR7 ( Add synonyms , Nomenclature history )

Gene Function:
transforming growth factor-beta receptor

Protein Function :
Receptor for activin A, activin B and inhibin A. Involved in transmembrane signaling.


InterPro :
Ser/Thr kinase AS , Kinase-like dom sf , Activin recp , Prot kinase dom [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-484012 XB-GENE-865037 XB-GENE-17332906
Gene Symbol acvr2a acvr2a.L acvr2a.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216172
399283
495087
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine acvr2a acvr2a.L acvr2a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ACVR2A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Acvr2a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Acvr2a Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR acvr2aa acvr2ab ZFIN Ensembl
chicken
GEISHA ACVR2A Ensembl
fruit fly
Publications
First Activin receptor mRNA is expressed early in Xenopus embryogenesis and the level of the expression affects the body axis formation., Biochem Biophys Res Commun 1991        
Most Recent Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage., Proc Natl Acad Sci U S A 2017                      
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 5 terms 5 terms
PANTHER acvr2a
KEGG Pathways K04670 K04670 K04670
KOG [T] Transforming growth factor beta/activin receptor subfamily of serine/threonine kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks acvr2a
ORFs acvr2a.L ORF1 acvr2a.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info