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Summary Expression Gene Literature (182) GO Terms (10) Nucleotides (125) Proteins (47) Interactants (303) Wiki
XB-GENEPAGE-484116
Gene Symbol:
hnf1a

Gene Name:
HNF1 homeobox A

Synonyms:
hnf1 , lfb1 , mody3 , XLFB1 , XLFB1b , XLFB1a , hnf1a-a , hnf1a-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreas and liver. Binds to the hepatocyte specific promoter element HP1. Binds to the inverted...[+]


InterPro :
HNF-1 N , HNF1b C , HNF1 dimer N dom sf , Homeobox dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
nonpapillary renal cell carcinoma [+]

OMIM:
TYPE 2 DIABETES MELLITUS; T2D [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-484117 XB-GENE-6252640 XB-GENE-865049
Gene Symbol hnf1a hnf1a.L hnf1a.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100144688
378590
378589
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hnf1a hnf1a.L hnf1a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HNF1A OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hnf1a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hnf1a Ensembl
zebrafish
ZFIN, AGR hnf1a ZFIN Ensembl
chicken
GEISHA HNF1A Ensembl
fruit fly
worm
Publications
First Liver-specific gene expression: A-activator-binding site, a promoter module present in vitellogenin and acute-phase genes., Mol Cell Biol 1991  
Most Recent Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Nat Cell Biol 2016                    
All View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 7 terms 7 terms
PANTHER hnf1a
KEGG Pathways K08036 K08036 K08036
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hnf1a
Antibodies Hnf1a Ab1 , Hnf1a Ab2 Hnf1a Ab1 , Hnf1a Ab2 Hnf1a Ab1 , Hnf1a Ab2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list