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Summary Expression Gene Literature (31) GO Terms (11) Nucleotides (106) Proteins (28) Interactants (303) Wiki
XB-GENEPAGE-484116

Gene Symbol: hnf1a

Gene Name: HNF1 homeobox A

Synonyms: hnf1 , lfb1 , mody3 , XLFB1 , XLFB1b , XLFB1a , hnf1a-a , hnf1a-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreas and liver. Binds to the hepatocyte specific promoter element HP1. Binds to the inverted...[+]

Interactants: Loading ...
Disease Ontology: nonpapillary renal cell carcinoma [+]

OMIM Diseases: DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM [+]

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Xenbase Gene ID XB-GENE-484117 XB-GENE-6252640 XB-GENE-865049
Gene Symbol hnf1a hnf1a.L hnf1a.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq TrEMBL TrEMBL NCBI Protein TrEMBL Swiss-Prot Refseq Swiss-Prot TrEMBL TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine hnf1a hnf1a.L hnf1a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HNF1A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Hnf1a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR hnf1a ZFIN Ensembl
chicken
GEISHA HNF1A Ensembl
fruit fly
worm
WORMBASE
Publications
First Liver-specific gene expression: A-activator-binding site, a promoter module present in vitellogenin and acute-phase genes., Mol Cell Biol 1991  
Most Recent Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Nat Cell Biol 2016                    
All View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 7 terms 8 terms
PANTHER hnf1a
KEGG Pathways K08036 K08036 K08036
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Hnf1a Ab1 , Hnf1a Ab2 Hnf1a Ab1 , Hnf1a Ab2 Hnf1a Ab1 , Hnf1a Ab2
Affymetrix 1.0 Str.38798.1.A1_at [+] Xl.21442.1.S1_at [+] Xl.1177.1.S1_at
Affymetrix 2.0 Xl2.45544.3.S1_at [+] Xl2.1177.1.A1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.2


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