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Summary Expression Gene Literature (181) GO Terms (30) Nucleotides (131) Proteins (42) Interactants (209) Wiki
XB-GENEPAGE-484247
Gene Symbol:
acvr2b

Gene Name:
activin A receptor type 2B

Synonyms:
activin type IIB receptor , actriib , actr-iib , XAR1 ( Add synonyms , Nomenclature history )

Gene Function:
transforming growth factor-beta receptor

Protein Function :
Receptor for activin A, activin B and inhibin A. Involved in transmembrane signaling.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
visceral heterotaxy

OMIM:
HETEROTAXY, VISCERAL, 4, AUTOSOMAL; HTX4

External Links:
 
Xenbase Gene ID XB-GENE-484248 XB-GENE-484252 XB-GENE-17330678
Gene Symbol acvr2b acvr2b.L acvr2b.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448641
399277
397859
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine acvr2b acvr2b.L acvr2b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ACVR2B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Acvr2b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Acvr2b Ensembl
zebrafish
ZFIN, AGR acvr2ba ZFIN Ensembl
chicken
GEISHA ACVR2B Ensembl
fruit fly
worm
Publications
First Cloning of a second type of activin receptor and functional characterization in Xenopus embryos., Science 1992  
Most Recent ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development., J Cell Biol 2019                    
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 30 terms 3 terms 4 terms
PANTHER acvr2b
KEGG Pathways K13596 K13596 K13596
KOG [T] Transforming growth factor beta/activin receptor subfamily of serine/threonine kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks acvr2b
ORFs acvr2b ORF1 XSTK2 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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