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Summary Expression Gene Literature (31) GO Terms (5) Nucleotides (114) Proteins (27) Interactants (177) Wiki
XB-GENEPAGE- 484247

Gene Symbol: acvr2b

Gene Name: activin A receptor type 2B

Synonyms: activin type IIB receptor , actriib , actr-iib , XAR1
Add Xenopus synonyms , Nomenclature history


Gene Function: transforming growth factor-beta receptor

Protein Function:
Receptor for activin A, activin B and inhibin A. Involved in transmembrane signaling.


Interactants: YYY

OMIM Disease Associations: HETEROTAXY, VISCERAL, 4, AUTOSOMAL; HTX4
 
Xenbase Gene ID XB-GENE-484248 XB-GENE-484252 XB-GENE-17330678
Gene Symbol acvr2b acvr2b.L acvr2b.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.4193 Xl.1053
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 3 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine acvr2b acvr2b.L acvr2b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ACVR2B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Acvr2b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN acvr2ba ZFIN Ensembl
chicken
GEISHA ACVR2B Ensembl
fruit fly
worm
WORMBASE
Publications
First: Cloning of a second type of activin receptor and functional characterization in Xenopus embryos. [Science 1992]
Most recent: Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. [Proc Natl Acad Sci U S A 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 4 terms 0 term
EC now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
PANTHER acvr2b
KEGG Pathways K13596 K13596
KOG [T] Transforming growth factor beta/activin receptor subfamily of serine/threonine kinases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 3 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Affymetrix 1.0 Str.4193.1.S1_at Xl.1053.1.S1_at
Affymetrix 2.0 Xl2.1053.1.S1_at

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