pdgfa Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (54)

Nucleotides (88)

Interactants (101)

XB-GENEPAGE-484494

Gene Symbol: pdgfa Gene Name: platelet-derived growth factor alpha polypeptide Synonyms: pdgf, pdgf-a Add Xenopus synonyms Gene Function: growth factor Interactants: tgfb1(9) , mapk1(7) , fgf2(4) , fgfr1(4) , fn1(4) , has2(4) , pik3ca(4) View All

XB-GENE-484495

XB-GENE-484499

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001170497\|Xenopus (Silurana) tropicalis platelet-derived growth factor alpha polypeptide (pdgfa), mRNA GGGGAGGGGGTGCAGAAGGAGCTCCGGCAGACAGGTGATGGGCGTTTCAGTGGATACGTTGGGCTGATCTGAGCGCTAAACATGCACATTCTGCGCCTCATCCACTGCTGAAGGCGCCCAACCATCAGCCAGCGAAACCTGGGGGAAAGGGGGTCTATAGTGGATACACCTAAAACAAACCTGCGCCTTATCTGCCGCTTTCCTGGGCTGTTGTTTTGCCCCTAAGGGATGGTACTGACTCCCCCAGCTACAGGAGCGGGTCTGCGGCTCCTACTGCAAAACGTTGCATTGTCATTGAGCAGAAATCGCAGCAGGACGCAATGAGGATCTGGGCTTGGATTCTGCTGCTAAGCGTCTGCTGCTACCTGTCTCCTTCATTGGGCGAGGAAGCAGAGATCCCCCAGGAGCTGATCGAGAGGCTGGCTCACAGCGAAATCCGCAGCATCAGCGACCTGCAGCGTCTCCTGGACATTGATTCCGTAGGAGGAGGCGAGGATGCTTCTGGAGCCAACATAAGATCACAAACACGCGACTTTCGCCATAATAGGCTTGTGCCAGAGAAGCGTTCTGTTCCCAGTCGCAGAAAAAGAAGTGTTGAAGAAGCAGTTCCTGCTATCTGTAAAACAAGAACTGTTATATACGAGATACCTCGTAGCAAAATTGATTCGACATCTGCCAATTTTCTAATCTGGCCTCCGTGTGTGGAGGTGAAACGATGTACGGGATGCTGCAACACCAGCAGTGTCAAGTGCCAGCCATCAAGGATACACCACAGGAGTGTCAAGGTGGCAAAAGTAGAATATGTAAGAAAGAAACCCAAATTAAAAGAAGTTCTTGTGCAGTTAGAGGAACATCTGGAATGCACGTGTACAGCAAACTCTAATTCAGATTATCGAGAAGAAGAAACCGAAAGACAGGAAAAAAAAAACTTGTTCAAACGACACTCTGTGAGAACAAAGGAACAATGTACATTTCTTTAATGTGACATCAAAGCAAGTATTGCAGCACTCTTACAGAGAAGAGACCGCTTCCCCTGTCAGAAAAACTGCAGCAACAAAACAAGATGGCGGATGGCTGAAAGAAGGATATCACATTAAAAAAGTACTGCAAACCATAGGGATTGAATAGAGGCCTGATGTCCAAGCAACGGTGCTTTATGTCAAGAGATGTGCCTGCTTTTGCTGTTTTCAAGATGGATGTTTATTGATAGAAACATGGCAAAGAAAAGCCAGGAATGTATCAAATGAATGTGTCGACGCAGAAGCTACAAAAACAATGCATCCTTGCTCAGTGGTGTTTAAAGTCTTCACAAAAACCTGGGAAGCCTTAAGTGGACTTTTTTTTTTAATTAAACATAGCGTAACTATTAAGCTTTGGGGTAAATAAAGTATAACAGCACCATCCTAGCACTAAGCAGCCATCTGCCTCTATAGTGGTCGATGACTGCTAGACATAGCCTAGTCCTATTGGGCAGAGGAAGAGCTCTCTAGTGTTGGATTTGTTTTAGGTGGATTCACTCTTGCTGGTTATGCAGGTATAAAATATTCGATTAAATAATAAAAAAAAAAAAAAAA	Refseq >NM_001087835\|Xenopus laevis platelet-derived growth factor alpha polypeptide (pdgfa), mRNA GAATTCCGGCAGCGTTGTGGATTGTTCGCATTGGCCGATCAGGTGCGACTGCAGAGACGCCAGTGTGTTCCATCTGCCGCAAAGGGAGCCGCTGTTCGTGTTTGGAAAGTTCATTCACCCTGCTCTTTGCCTGCTTTGTGCTAATAACGCTGGATTGAGAGGCGGCGCAGAAGGAGACAGGTGATGGGCGTTTCACTGGATCCGTTGGGCTGATCCGAGCGCTAAACCATGCGCATCCTGCGCCTCATCCTCTGCTGAAGCCTCAGCCGGCCGAGTGGATTTAGAAAGCTGCGATTTGCTGGGCTGTTGTTTTGCCCTGAGGGATGTTACTGACTCCCCCGGCTACAGGAGCGGGTCTGCGGCTCCTACTGCAAAACGTTGCGTTGTCATTGAGCAGAAATCGCAGCAGGACGCAATGAGGATCTGGGCTTGGATTCTGCTGCTAAGCGTCTGCTGCTCTTACCTGTCTCCTTCATTGGGCGAGGAAGCAGAGATCCCCCAGGAGCTGATCGAGAGGCTGGCTCACAGCGAAATCCGCAGCATCAGCGACCTGCAGCGTCTCCTGGACATTGATTCCGTAGGAGGAGGCGAGGATGCTTCTGCAGCCAACATAAGATCACAAAAACACGACTTCCATCATAATAGGCTGGTGCCAGAAAAGCGCTCCGTTCCCAGTCGCAGAAAAAGAAGTGTTGAAGAAGCAGTCCCTGCTATCTGTAAAACAAGAACTGTTATATACGAGATACCTCGTAGCCAAATTGATCCAACATCTGCCAATTTTCTGATCTGGCCTCCATGCGTGGAGGTGAAACGATGCACGGGATGCTGCAACACCAGCAGTGTCAAGTGCCAGCCATCAAGGATACACCACAGGAGTGTCAAGGTGGCAAAAGTAGAATATGTAAGAAAGAAACCCAAATTAAAAGAAGTTCTTGTGCGGTTAGAGGAACATCTGGAATGCACGTGTACAGCAAATTCTAATTCAGATTATCGAGAAGAAGAAACTGGCTTTTTCACCAGCCCTGCCCTTGTGTTAACAGGAAGGACTAGGGAAACAGGTAAAAAACAGAAAAGAAAAAAACTAAAGCCAACTTAATAACCGTCTGGAAAGTAATTTTGAACGGCAGATGTGAGGTGAAAATAAGCTAGACAGGATCATCTGGGACTCGGATGTGTACGCCATGTTACATTCCCGAATCTTCTACGTATGGTGCTTTATTGACTGTTTCGTGTTTGTTCTCTTGTGCAGAAAGACAGGGAAAAAAAACTTGTTCAAACGCCACTCTGTGAGAACAAAGGAACAATGTGCATTTCTTTAATGTGACATCAAAGCAAGTATTGCAGCACTCTTACAGAGAAGAGACCGCTTCCCCTGTCAGAAAAAACTGCAGCAACAAATCAAGATGGTGGAAAGAAGGATATCACATTAAAAGTACTGCAAACAGATTGAATAGAGGCCTGATGTCCAAGCAATGGTGCTTTATGTCAAGAGATGTGCCTGCTTTTGCTGGTTTAAGATGGATATTGTTTGATGGAAACATGGCAAAGAAAAGCCAGGAATGTATCAAATGAATGTGTCTAAGCAGAAGCTACAAAAACAATGCATCCTTGCTCAGTGGTGTTTAAAGTCTTCACAAATACCTGGGAAGCCTTAAGTGGACTTTTTTTTTTAAATTAAACATAACGTACCTATTAAGCTTTGGGGTAGCATCCTAGCACTAAGCAACCGTCTGCCTCTTTAGCGGCCCATGAGTGCTAGACATAGGTCTAGTCCTATTGGGCAGAGGAAGAGTTCTATAGTGTTGGATTTGTTTTAGGTGGATTCACTCTTGCTGGCTATGCAGGTATAAAATATTCGATAATGTATCTATTATTTTGTAATTATTGTTGAAATTCCAACTTGACACTTGTTTCCGGAAATACAAAGAGCTGATGGTAG
Protein		Refseq >NP_001163968\|platelet-derived growth factor alpha polypeptide precursor [Xenopus (Silurana) tropicalis] MRIWAWILLLSVCCYLSPSLGEEAEIPQELIERLAHSEIRSISDLQRLLDIDSVGGGEDASGANIRSQTRDFRHNRLVPEKRSVPSRRKRSVEEAVPAICKTRTVIYEIPRSKIDSTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRIHHRSVKVAKVEYVRKKPKLKEVLVQLEEHLECTCTANSNSDYREEETERQEKKNLFKRHSVRTKEQCTFL	Refseq >NP_001081304\|platelet-derived growth factor subunit A precursor [Xenopus laevis] MRIWAWILLLSVCCSYLSPSLGEEAEIPQELIERLAHSEIRSISDLQRLLDIDSVGGGEDASAANIRSQKHDFHHNRLVPEKRSVPSRRKRSVEEAVPAICKTRTVIYEIPRSQIDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRIHHRSVKVAKVEYVRKKPKLKEVLVRLEEHLECTCTANSNSDYREEETGFFTSPALVLTGRTRETGKKQKRKKLKPT UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.25084	Xl.841 [+] Xl.73357
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	PDGFA
mouse		MGI	Pdgfa	All(2) Targeted, knock Out(1) Targeted, other(1)
zebrafish		ZFIN ZFIN	pdgfaa pdgfab

Publications
First:		[Growth factors and embryonic development] [Reprod Nutr Dev 1988]
Most recent:		PDGF-A controls mesoderm cell orientation and radial intercalation during Xenopus gastrulation. [Development 2011]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		growth factor activity
Biological:
Cellular Component:		membrane
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.4874.1.S1_x_at [+] Str.4874.1.S1_at	Xl.841.3.S1_a_at [+] Xl.841.1.S1_a_at
Affymetrix 2.0			Xl2.841.3.S1_a_at [+] Xl2.841.1.S1_a_at Xl2.15548.1.A1_at

Symbol legend[+]