sox3 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (122)

Nucleotides (561)

Interactants (396)

XB-GENEPAGE-484814

Gene Symbol: sox3 Gene Name: SRY (sex determining region Y)-box 3 Synonyms: xSox3, Sry, Xtsox3, Xlsox3 Add Xenopus synonyms Gene Function: HMG-box transcription factor Interactants: sox2(38) , sox13(31) , snai2(30) , otx2(24) , tubb2b(24) , nog(21) , myc(19) View All	1/6

XB-GENE-484815

XB-GENE-484819

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001007501\|Xenopus (Silurana) tropicalis SRY (sex determining region Y)-box 3 (sox3), mRNA GCAGGAGTTAGGGAAGTTTGTGCCGGGATCTGTGTGGCAGAGCAGCTTCATTTTCTCCCGTGCAGTGTCTCCTCCACCTGCAGCTCCAGATGTATAGCATGTTGGACACAGACCTCAAGAGCCCGGTGCAGCAGAGCAATGCACCGAACGGGGGCCCCGGCACCCCAGGGGGCAAAGGCAATGCTTCTATCCCGGATCAGGAGCGGGTGAAACGGCCGATGAACGCGTTTATGGTGTGGTCCCGGGGCCAGCGGAGAAAGATGGCCCAGGAGAACCCCAAGATGCACAACTCGGAGATCAGTAAGAGGCTGGGGGCTGACTGGAAGTTGTTGAGCGATTCCGAGAAAAGACCCTTCATCGACGAGGCCAAGAGGCTGAGAGCAGTCCATATGAAGGAGTACCCGGATTACAAGTACAGACCCCGCAGGAAGACCAAGACCCTCCTGAAAAAGGACAAGTATTCCCTGCCTGGCAACCTTTTGGCTCCAGGAGTTAGCCCGGTGGCCAGCAGTGTTGGTGTTGGCCAGAGGATAGACACTTATGCTCACATGAATGGCTGGACTAATGGGGCTTATTCCCTGATGCAGGACCAGCTGGGCTACAGCCAGCACCCTGGGATGAACAGCCCCCAGATGCAGCAGATCCAGCACAGGTATGACATGGGCGGCCTGCAGTACAGCCCAATGATGTCCTCCGCGCAAACTTACATGAATGCTGCTGCCTCTACCTATAGCATGTCCCCTGCCTACAACCAGCAGAGCTCCACGGTCATGAGTTTGGGCTCTATGGGCTCAGTGGTGAAATCCGAACCCAGCTCCCCCCCTCCAGCCATCACCTCCCACACGCAAAGGGCCTGCCTGGGAGACCTGCGAGATATGATCAGCATGTACCTGCCCCCAGGTGGAGATGCCAGCGACCCTTCTTCCCTTCAGAGTAGCAGACTGCACAGTGTACACCAACATTACCAGAGCGCAGCTGGCCCCAATGGCACTGTACCGCTCACTCACATATAACACTTTTGCTTCTGCTCTTTTCTAAAGACGCTTTGCTTGCCTGGCAAGTATCAGACTGAATTAAAAAAAGACCCACTTGAGGACAATGAATCAAGGGTGTATTTTGTACAAAAGTTTGCGCAAACTTCCTTTATAGAGCACAATATTTTATGTACTTTTTGTTGGGGGGGGGATTATGTGTTGGGGCTTTTAAAATCCAGAGGTTCCAGGTGTTCTTTATCCCATTTACACGTACCTGGTACCTTCAGTTGTACAAGTCGGGACGATCTTAACCATAACATGTTTACACGTTTTAATGACACGCTCAAGATTTCCTTGGGTTTTATCCAAAACTGTAGATTTTATCGTTTGCATATTTTTTTTTTTTTAGACTTGACTTTTCAAAAGAGCTGTGCGGGTCGCAAACAGGACTTTTATTTTGTTTTCTTTTAATTTATAGTATGTATTTTTTTTTTTTTCCTCCATGTGAAATCGCCTTTTTTTCTGGCTCATATTTACTGTGAATTGTTTAACATATCAACAACAAATACTTTAGAATTGTTTTACTGGGTTTCTAAAGACTTTGACATGAAAGTAAAACGACATACTCAATAAATTTTCTATGAGGAATGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001090679\|Xenopus laevis SRY (sex determining region Y)-box 3 (sox3), mRNA ACACTAGTGGAAAGGAAAGTTTTGAGTTGGAATCTGTGTGGCTGTTCAGCGCTTTCTCGTGCAGTTTCCCACCTGCAGCTCCAAATGTATAGCATGTTGGACACCGACATCAAGAGCCCCGTGCAGCAGAGCAATGCACCGATCGGGGGCCCCGCTACTCCGGGGGGCAAAGGCAACGCTTCCACCCTGGATCAGGATCGGGTGAAGCGCCCGATGAACGCGTTTATGGTTTGGTCCCGGGGCCAGCGAAGAAAGATGGCCCAGGAGAACCCCAAGATGCACAACTCGGAGATCAGCAAAAGATTGGGCGCTGACTGGAAGCTGCTCAGCGATTCCGACAAAAGACCCTTCATCGACGAGGCCAAGAGGCTGAGAGCTGTGCACATGAAAGACTACCCGGATTACAAGTACCGACCCCGTAGGAAGACCAAGACTCTCCTGAAGAAGGACAAGTATTCTCTTCCCGGCAACCTCTTGGCTCCAGGAGTAAGCCCGGTGGCTAGCAGTGTCGGAGTGGGCCAGAGGATAGACACTTACGCGCACATGAACGGCTGGACTAATGGCGCTTATTCCCTGATGCAGGACCAGTTGGGCTACAGCCAACACCCGGCCATGAACAGCCCCCAGATGCAGCAGATCCAGCACAGGTATGACATGAGCGGCCTCCAGTACAACCCTATGATGACCTCTGCCCAAAATGCCTACATGAATGCCGCTGCCTCCACCTACAGCATGTCCCCTGCCTACAACCAGCAGAGCTCCACGGTCATGAGCTTGGCTTCCATGGGCTCAGTGGTGAAATCCGAACCCAGCTCCCCCCCTCCAGCCATCACCTCCCACACACAGAGGGCCTGCCTGGGAGACCTGCGAGATATGATCAGCATGTACCTGCCCCCAGGTGGAGACGCCAGCGACCCTTCACTTCAAAATAGCAGACTGCACAGTGTACACCAACACTACCAGAGTGCCGCCGGCCCTGGAGTCAATGGCACGGTACCGCTCACTCACATATAACACTTTGTGCCCTTTGCTAAAGACGCTTTACTTGCCTGCTGGCAACTATCAGACTGCCGCATAAAACATTTAAAAAAAAAAATCCACTTGAGGACAATGAATCAGGGTGTAATTTTGTACAAACGTTTGCGCAAACTTCCTTTTTATAGAGCACAATATTTTATGTACTTTTTGTTTGGGGGGGGTAGGGATGATGTGTTGGGCTTTCAAAAACCCAGGGACTCTAGATGTCCTTTTTATCCCATTGACAAGGACCTGGTAACCTTCACTTGTACAAGTTGTGATGTTCTTAACCATAACTCGATGTTTACACGTTTTAACGACACGCTCAAGATTTACTTGGGTTTTTATCCAAAACTGTAGATTTTTCGTTTGCATTTTTTTTAGACTTTACAAAAAAGCTGTGCGGGTCGCAAACAGGACTTTTTGTTTTGTTCTTTTAACTTATAGTATGTATATATTTTGTGAAATCCACTTTTTTCCCCCTTTGGTTCGTATTTACTGTGAATTGTTTAACATATCAACCCACAAATGCTTTAGATTGTTTTACTGGGTTTCTAAAGACTTTGACATGAAAGTAAACGACATACTCAATAAATTTTTCTATGAGGAATGTAAAAAAAAAAAA
Protein		Refseq >NP_001007502\|transcription factor Sox-3 [Xenopus (Silurana) tropicalis] MYSMLDTDLKSPVQQSNAPNGGPGTPGGKGNASIPDQERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGNLLAPGVSPVASSVGVGQRIDTYAHMNGWTNGAYSLMQDQLGYSQHPGMNSPQMQQIQHRYDMGGLQYSPMMSSAQTYMNAAASTYSMSPAYNQQSSTVMSLGSMGSVVKSEPSSPPPAITSHTQRACLGDLRDMISMYLPPGGDASDPSSLQSSRLHSVHQHYQSAAGPNGTVPLTHI UniProtKB	Refseq >NP_001084148\|transcription factor Sox-3-A [Xenopus laevis] MYSMLDTDIKSPVQQSNAPIGGPATPGGKGNASTLDQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSDKRPFIDEAKRLRAVHMKDYPDYKYRPRRKTKTLLKKDKYSLPGNLLAPGVSPVASSVGVGQRIDTYAHMNGWTNGAYSLMQDQLGYSQHPAMNSPQMQQIQHRYDMSGLQYNPMMTSAQNAYMNAAASTYSMSPAYNQQSSTVMSLASMGSVVKSEPSSPPPAITSHTQRACLGDLRDMISMYLPPGGDASDPSLQNSRLHSVHQHYQSAAGPGVNGTVPLTHI UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.27268 [+] Str.5490 Str.24709 Str.45786 Str.68199 Str.79793	Xl.22
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		129 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SOX3	OMIM:300123 OMIM:312000
mouse		MGI	Sox3	All(3) Targeted, knock Out(1) Targeted, other(2)
zebrafish		ZFIN	sox3	4 Lines(s)

Publications
First:		Blastoderm-specific and read-through transcription of the sry alpha gene transformed into the Drosophila genome. [Dev Biol 1986]
Most recent:		Primary oocyte transcriptional activation of aqp1ab by the nuclear progestin receptor determines the pelagic egg phenotype of marine teleosts. [Dev Biol 2013]
		View All Papers 33 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:
EC:
KOG:		[K] HMG-box transcription factor

Reagents		tropicalis	laevis
Clones		EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.27268.1.S1_at [+] Str.36456.1.A1_x_at Str.45786.1.A1_at Str.24709.1.A1_x_at Str.5490.1.A1_x_at	Xl.22.1.S1_at
Affymetrix 2.0			Xl2.22.1.S1_at

Symbol legend[+]