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Summary Expression Gene Literature (51) GO Terms (14) Nucleotides (125) Proteins (34) Interactants (519) Wiki
XB-GENEPAGE- 484864

Gene Symbol: sox17b.1

Gene Name: SRY (sex determining region Y)-box 17 beta, gene 1

Synonyms: Xsox17-beta , sox17-beta , tSox17beta , Sox17beta , sox17 , Xsox17
Add Xenopus synonyms , Nomenclature history


Gene Function: HMG-box transcription factor

Protein Function :
Transcription activator. Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'. All of the sox17 proteins are required for embryonic endoderm development and gas...[+]


Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations:
1/5
 
Xenbase Gene ID XB-GENE-484865 XB-GENE-17344356 XB-GENE-6252148
Gene Symbol sox17b.1 sox17b.1.L sox17b.1.S
Chromosome Chr06 chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.7017 Xl.44
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 24 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine sox17b.1 sox17b.1.L sox17b.1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM, MalaCards, KEGG Disease, DECIPHER Protein Atlas, Allen Brain Atlas
mouse
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
fruit fly
worm
WORMBASE
Publications
First: Xsox17alpha and -beta mediate endoderm formation in Xenopus. [Cell 1997]
Most recent: Tbx2 is required for the suppression of mesendoderm during early Xenopus development. [Dev Dyn 2018]
View All Papers 11 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 13 terms
PANTHER sox17b.1
KEGG Pathways K04495
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino sox17b.1 MO1 sox17b.1 MO1 sox17b.1 MO1
ORF sox17b.1.S ORF1
Affymetrix 1.0 Str.7017.1.S1_at Xl.44.1.S1_s_at [+]
Affymetrix 2.0 Xl2.44.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556