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Summary Expression Gene Literature (218) GO Terms (24) Nucleotides (223) Proteins (14) Interactants (1036) Wiki
XB-GENEPAGE- 484970

Gene Symbol: cer1

Gene Name: cerberus 1, DAN family BMP antagonist

Synonyms: xcer , xcer-1 , xcer1 , cer , Cerberus , tCerberus , cer-1 , dand4
Add Xenopus synonyms , Nomenclature history


Gene Function: secreted BMP antagonist

Protein Function:
Inhibits wnt, nodal/nr-1 and bmp signaling in the embryo to promote head formation and anterior neural induction. Within the endoderm, acts as an essential mediator of nodal/nr-1-induced cardiogenesis ...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/4
 
Xenbase Gene ID XB-GENE-484971 XB-GENE-17332002 XB-GENE-865019
Gene Symbol cer1 cer1.L cer1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.1865 Xl.368 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 71 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cer1 cer1.L cer1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CER1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Cer1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
GEISHA CER1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The onset of activation responsiveness during maturation coincides with the formation of the cortical endoplasmic reticulum in oocytes of Xenopus laevis. [Dev Biol 1984]
Most recent: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. [Dev Cell 2017]
View All Papers 59 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 0 term 19 terms
EC
PANTHER cer1
KEGG Pathways K01645 K01645
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)   EXRC - 5 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino cer1 MO1 , cer1 MO2 , cer1 MO3 , cer1 MO4 cer1 MO1 , cer1 MO2 , cer1 MO3 , cer1 MO4 cer1 MO1 , cer1 MO2 , cer1 MO3 , cer1 MO4
ORF cer1 ORF1
Affymetrix 1.0 Str.1865.1.S1_at Xl.368.1.S1_at
Affymetrix 2.0 Xl2.368.1.S1_at [+]

Symbol legend[+]

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