cer1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (144)

Nucleotides (220)

Interactants (423)

XB-GENEPAGE-484970

Gene Symbol: cer1 Gene Name: cerberus 1, DAN family BMP antagonist Synonyms: xcer, xcer-1, xcer1, cer, Cerberus, tCerberus, cer-1, dand4 Add Xenopus synonyms Gene Function: secreted BMP antagonist Interactants: chrd(55) , nodal(54) , gsc(43) , t(40) , otx2(31) , nog(29) , bmp4(25) View All	1/2

XB-GENE-484971

XB-GENE-865019

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203515\|Xenopus (Silurana) tropicalis cerberus 1, cysteine knot superfamily (cer1), mRNA TGGAAGGGCAAGTTGCTCAGAATCATTGCAAGGTCGGGATATTATACAATGTTACTCTGTGTACTTAAGATCTACATTATTTTCTGCCTTGTGAATGATGGAGCAGGAAAACGCTCAGAAGTACGAGGAAGGACAAAAACATATTCACATAACAGCAGAGGTTACTTCAGAAAAGAAAGGGGAATGGGAAAAAACAAGATACTGGTGGTGAATACTAAAGGTTTTGATCAACCCCACATTGGGCAAGGTAGTTTTGGTTTAGTAGCTGAACTTTTTGATTCCACCAGGACAGATACAAGTAGAAAAGAGCCAGACATTAACAAAGTCAAGCTTTTCTCAACAGCTGCCCACGCAAACAAAAGTTCAAGGAATATAGGCATTTTTAGGAGAAAAGCTTTCAATGGTTCTAGAAGGAATATTTTTTCTCGCCAACCATTTAATAAAAGAAATACCGATGTTACTGAAAAGCCTGGTGCCAAGATGTTCTGGAACAATTTTTTGGTGAAAATGAATGGAGCTCCACAGAATACAAGCCATGGCGGTAAACCACAGGAGATAATGAAGGAAGCTTGCAAGACCTTGCCCTTTACTCAAAACATTGTGCATGAAAACTGTGACAGGATGGTGATACAGAACAATCTGTGCTTTGGTAAATGTATCTCTCTCCATGTTCCAAATCAGCAAGATCGCCGAAATACATGTGCCCACTGCTTGCCATCCAAATTTACTCTGAACCACCTGGCACTGAATTGTACCGGATCTAACAATGTGGTGAAGGTTGTCATGATGGTAGAGGAATGTGCATGTGAAGCTCATAAGAACAACTATCACCAAACTGCACAATTCAACATGGATGCATCTACCACCCTGCACAATTAAAAGGACCGACATATGTAAATGCCATTTTGTATATTTTTCACATACAACTAAGAAAAAGCATTACTTTGCCCCCTGTTTCATATGTCTACAAGGAAAAAGAATTCCACCAATAATAATGACCAAGAAGCGATTTGTATAACTTTCAAGGTACCAGTCTCCTCTGGAGTTATTGTGTATAAATTCATAAAATCCTGATTCTACAAACAATTTTCAGGCAACCCAGACAAAATCTTTTTGACTTTTTAACAAAATGAATACCCAAATATATGTTAAGATAATGTGGTTACGTGTAACTAAATATTCAAGATTATTAGTGTGTTTTTTGCGTGCAGATTTAATTGTATTTATTTCATTGTGACAATGAAGAGAATGTCTATTAAAAAACATTTTTATGTTTACTACACTTTTAAAAAAAAAAAAAA	Refseq >NM_001088331\|Xenopus laevis cerberus 1, cysteine knot superfamily (cer1), mRNA CTAAAAGCGGCACAGTGCAGGAACAGCAAGTCGCTCAGAAACACTGCAGGGTCTAGATATCATACAATGTTACTAAATGTACTCAGGATCTGTATTATCGTCTGCCTTGTGAATGATGGAGCAGGAAAACACTCAGAAGGACGAGAAAGGACAAAAACATATTCACTTAACAGCAGAGGTTACTTCAGAAAAGAAAGAGGAGCACGTAGGAGCAAGATTCTGCTGGTGAATACTAAAGGTCTTGATGAACCCCACATTGGGCATGGTGATTTTGGCTTAGTAGCTGAACTATTTGATTCCACCAGAACACATACAAACAGAAAAGAGCCAGACATGAACAAAGTCAAGCTTTTCTCAACAGTTGCCCATGGAAACAAAAGTGCAAGAAGAAAAGCTTACAATGGTTCTAGAAGGAATATTTTTTCTCGCCGTTCTTTTGATAAAAGAAATACAGAGGTTACTGAAAAGCCTGGTGCCAAGATGTTCTGGAACAATTTTTTGGTTAAAATGAATGGAGCCCCACAGAATACAAGCCATGGCAGTAAAGCACAGGAAATAATGAAAGAAGCTTGCAAAACCTTGCCCTTCACTCAGAATATTGTACATGAAAACTGTGACAGGATGGTGATACAGAACAATCTGTGCTTTGGTAAATGCATCTCTCTCCATGTTCCAAATCAGCAAGATCGACGAAATACTTGTTCCCATTGCTTGCCGTCCAAATTTACCCTGAACCACCTGACGCTGAATTGTACTGGATCTAAGAATGTAGTAAAGGTTGTCATGATGGTAGAGGAATGCACGTGTGAAGCTCATAAGAGCAACTTCCACCAAACTGCACAGTTTAACATGGATACATCTACTACCCTGCACCATTAAAAGGACTGTCTGCCATACAGTATGGAAATGCCCATTTGTTGGAATATTCGTTACATGCTATGTATCTAAAGCATTATGTTGCCTTCTGTTTCATATAACCACATGGAATAAGGATTGTATGAATTATAATTAACAAATGGCATTTTGTGTAACATGCAAGATCTCTGTTCCATCAGTTGCAAGATAAAAGGCAATATTTGTTTGACTTTTTTCTACAAAATGAATACCCAAATATATGATAAGATAATGGGGTCAAAACTGTTAAGGGGTAATGTAATAATAGGGACTAACAACCAATCAGCAGGTATGATTTACTGGTCACCTGTTTAAAAGCAAACATCTTATTGGTTGCTATGGGTTACTGCTTCTGGGCAAAATGTGTGCCTCATAGGGGGGTTAGTGTGTTGTGTACTGAATTAATTGTATTTATTTCATTGTTACAATGAAGAGGATGTCTATGTTTATTTCACTTTTATTAATGTACAATAAATGTTCTTGTTTCTTTAAAAAAAAAAAAAAA
Protein		Refseq >NP_988846\|cerberus precursor [Xenopus (Silurana) tropicalis] MLLCVLKIYIIFCLVNDGAGKRSEVRGRTKTYSHNSRGYFRKERGMGKNKILVVNTKGFDQPHIGQGSFGLVAELFDSTRTDTSRKEPDINKVKLFSTAAHANKSSRNIGIFRRKAFNGSRRNIFSRQPFNKRNTDVTEKPGAKMFWNNFLVKMNGAPQNTSHGGKPQEIMKEACKTLPFTQNIVHENCDRMVIQNNLCFGKCISLHVPNQQDRRNTCAHCLPSKFTLNHLALNCTGSNNVVKVVMMVEECACEAHKNNYHQTAQFNMDASTTLHN UniProtKB	Refseq >NP_001081800\|cerberus precursor [Xenopus laevis] MLLNVLRICIIVCLVNDGAGKHSEGRERTKTYSLNSRGYFRKERGARRSKILLVNTKGLDEPHIGHGDFGLVAELFDSTRTHTNRKEPDMNKVKLFSTVAHGNKSARRKAYNGSRRNIFSRRSFDKRNTEVTEKPGAKMFWNNFLVKMNGAPQNTSHGSKAQEIMKEACKTLPFTQNIVHENCDRMVIQNNLCFGKCISLHVPNQQDRRNTCSHCLPSKFTLNHLTLNCTGSKNVVKVVMMVEECTCEAHKSNFHQTAQFNMDTSTTLHH UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.1865	Xl.368 [+] Xl.33990
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		57 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CER1
mouse		MGI	Cer1	All(7) Targeted, knock Out(2) Targeted, other(5)
zebrafish

Publications
First:		The onset of activation responsiveness during maturation coincides with the formation of the cortical endoplasmic reticulum in oocytes of Xenopus laevis. [Dev Biol 1984]
Most recent:		Optimal histone H3 to linker histone H1 chromatin ratio is vital for mesodermal competence in Xenopus. [Development 2013]
		View All Papers 35 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones		EXRC - 2 clone(s)	EXRC - 5 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.1865.1.S1_at	Xl.368.1.S1_at
Affymetrix 2.0			Xl2.368.1.S1_at [+] Xl2.33990.2.A1_at Xl2.33990.1.S1_at

Symbol legend[+]