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Summary Expression Gene Literature (63) GO Terms (33) Nucleotides (77) Proteins (39) Interactants (623) Wiki
XB-GENEPAGE-484998
Gene Symbol:
wt1

Gene Name:
WT1 transcription factor

Synonyms:
xwt1 , wt-1 , Xwt-1 , wt1-b , wt1-a ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger transcription and splicing factor

Protein Function :
Transcription factor required for development of the vascular component of the pronephric kidney, the glomus; may repress tubule-specific gene expression in the portion of the pronephros fated to form ...[+]


InterPro :
CASTOR1 N , CASTOR fam , CASTOR1 , CASTOR ACT dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Frasier syndrome [+]

OMIM:
ANIRIDIA 1; AN1 [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-484999 XB-GENE-6252376 XB-GENE-864792
Gene Symbol wt1 wt1.L wt1.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216184
378664
373588
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine wt1 wt1.L wt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards WT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wt1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wt1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR wt1a wt1b ZFIN Ensembl
chicken
GEISHA WT1 Ensembl
fruit fly
worm
Publications
First Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA., Cytogenet Cell Genet 1995  
Most Recent Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome., Cell 2019                                  
All View All Papers 18 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 30 terms 13 terms 16 terms
PANTHER wt1
KEGG Pathways K09234 K09234 K09234
KOG [K] C2H2-type Zn-finger protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks wt1
Mutants Xtr.wt1emHorb
Morpholinos (on-target & off-target) wt1 MO1 , wt1 MO3 , wt1 MO4
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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