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Summary Expression Gene Literature (22) GO Terms (13) Nucleotides (151) Proteins (48) Interactants (300) Wiki
XB-GENEPAGE-485008
Gene Symbol:
mmp1

Gene Name:
matrix metallopeptidase 1

Synonyms:
xcol4 , collagenase-4 , MMP-18 , col4 , mmp18 ( Add synonyms , Nomenclature history )

Gene Function:
extracellular matrix metalloprotease

Protein Function :
Cleaves collagen type I. May play a role in larval tissue degeneration and adult organogenesis during amphibian metamorphosis. May be involved in tail resorption.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
recessive dystrophic epidermolysis bullosa [+]

OMIM:
PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; COPD [+]

External Links:
1/4
 
Xenbase Gene ID XB-GENE-485009 XB-GENE-17333196 XB-GENE-856365
Gene Symbol mmp1 mmp1.L mmp1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 594916
108708733
495287
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mmp1 mmp1.L mmp1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MMP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mmp1a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mmp1 Ensembl
zebrafish
chicken
GEISHA MMP1 Ensembl
fruit fly
FLYBASE Mmp1 Ensembl
worm
Publications
First Identification and characterization of a novel collagenase in Xenopus laevis: possible roles during frog development., Mol Biol Cell 1996  
Most Recent The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation., Development 2020                                      
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 13 terms 4 terms 5 terms
PANTHER mmp1
KEGG Pathways K01388 K01388 K01388
KOG [OW] Gelatinase A and related matrix metalloproteases
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks mmp1
Morpholinos mmp1 MO1 mmp1 MO1 mmp1 MO1
ORFs mmp1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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